Protein: BBX
HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2)

Gene: BBX
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q8WY36

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

282240

SEGN
Secretagogin

3

0

High-throughput

0.638

High

848096

MECP2
Methyl-CpG-binding protein 2

2

10

High-throughput

0.628

High

1038578

HDAC1
Histone deacetylase 1

2

16

High-throughput

0.628

High

1264302

ZSC31
Zinc finger and SCAN domain-containing protein 31

2

10

High-throughput

0.628

High

1264303

ZN512
Zinc finger protein 512

2

6

High-throughput

0.628

High

1264313

H2AW
Core histone macro-H2A.2

2

4

High-throughput

0.628

High

1264316

ARI1
E3 ubiquitin-protein ligase ARIH1

2

1

High-throughput

0.628

High

626211

APC
Adenomatous polyposis coli protein

1

20

High-throughput

0.618

High

1264307

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

3

8

High-throughput

0.609

High

1139158

RSBN1
Lysine-specific demethylase 9

2

0

High-throughput

0.602

High

918558

H2B1C
Histone H2B type 1-C/E/F/G/I

2

2

High-throughput

0.584

High

935045

H31
Histone H3.1

2

12

High-throughput

0.584

High

971520

RL18A
Large ribosomal subunit protein eL20

2

1

High-throughput

0.574

High

1264301

TRI44
Tripartite motif-containing protein 44

2

5

High-throughput

0.574

High

370101

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

395340

A4
Amyloid-beta precursor protein

2

5

High-throughput

0.550

High

71196

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

11

High-throughput

0.536

High

180395

MAGB2
Melanoma-associated antigen B2

1

6

High-throughput

0.536

High

257813

SIN3B
Paired amphipathic helix protein Sin3b

1

7

High-throughput

0.536

High

401014

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.536

High

617617

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.536

High

666499

ARI4A
AT-rich interactive domain-containing protein 4A

1

20

High-throughput

0.536

High

736616

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.536

High

773476

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.536

High

801275

KI67
Proliferation marker protein Ki-67

1

10

High-throughput

0.536

High

899283

RL15
Large ribosomal subunit protein eL15

1

1

High-throughput

0.536

High

911197

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.536

High

944875

RED1
Double-stranded RNA-specific editase 1

1

9

High-throughput

0.536

High

1019850

ILF3
Interleukin enhancer-binding factor 3

1

13

High-throughput

0.536

High

1045645

NOG2
Nucleolar GTP-binding protein 2

1

4

High-throughput

0.536

High

1050730

FHL2
Four and a half LIM domains protein 2

1

9

High-throughput

0.536

High

1193003

ZN467
Zinc finger protein 467

1

5

High-throughput

0.536

High

1264300

ZN653
Zinc finger protein 653

1

4

High-throughput

0.536

High

1264310

SENP3
Sentrin-specific protease 3

1

2

High-throughput

0.536

High

1264312

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

92277

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.533

High

721030

RFA3
Replication protein A 14 kDa subunit

2

3

High-throughput

0.533

High

791814

HD
Huntingtin

1

2

High-throughput

0.515

High

1264308

TRI54
Tripartite motif-containing protein 54

1

7

High-throughput

0.494

High

273186

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.489

High

615448

KALM
Anosmin-1

1

1

High-throughput

0.489

High

672709

CD6
T-cell differentiation antigen CD6

1

3

High-throughput

0.489

High

802164

NOP2
Probable 28S rRNA

1

2

High-throughput

0.489

High

805743

RL27A
Large ribosomal subunit protein uL15

1

1

High-throughput

0.489

High

806615

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.489

High

846502

BLK
Tyrosine-protein kinase Blk

1

4

High-throughput

0.489

High

908051

RS16
Small ribosomal subunit protein uS9

1

4

High-throughput

0.489

High

1029021

SRSF6
Serine/arginine-rich splicing factor 6

1

15

High-throughput

0.489

High

1264305

CC85A
Coiled-coil domain-containing protein 85A

1

1

High-throughput

0.489

High

347451

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

360221

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

13

High-throughput

0.479

High

379661

MYCN
N-myc proto-oncogene protein

1

11

High-throughput

0.479

High

432113

HS90A
Heat shock protein HSP 90-alpha

1

6

High-throughput

0.479

High

438400

HS90B
Heat shock protein HSP 90-beta

1

6

High-throughput

0.479

High

442347

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

10

High-throughput

0.479

High

455705

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.479

High

472905

H2AB2
Histone H2A-Bbd type 2/3

1

1

High-throughput

0.479

High

489180

H14
Histone H1.4

1

1

High-throughput

0.479

High

523900

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.479

High

553302

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

622496

CCND1
G1/S-specific cyclin-D1

1

1

High-throughput

0.479

High

642974

S10A4
Protein S100-A4

1

8

High-throughput

0.479

High

651807

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

828324

CENPA
Histone H3-like centromeric protein A

1

12

High-throughput

0.479

High

890772

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.479

High

916730

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.479

High

917661

H4
Histone H4

1

3

High-throughput

0.479

High

952505

H33
Histone H3.3

1

12

High-throughput

0.479

High

997832

RBBP4
Histone-binding protein RBBP4

1

20

High-throughput

0.479

High

1027152

CBX3
Chromobox protein homolog 3

1

12

High-throughput

0.479

High

1046645

KLF9
Krueppel-like factor 9

1

16

High-throughput

0.479

High

1067072

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1188629

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1221604

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1264299

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1264306

KLF16
Krueppel-like factor 16

1

16

High-throughput

0.479

High

1264311

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1264315

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

182846

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

652936

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

722467

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

750381

COIL
Coilin

1

0

High-throughput

0.458

High

1264304

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

4

High-throughput

0.457

High

179748

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.437

High

844654

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.437

High

894262

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.437

High

991534

SPAG1
Sperm-associated antigen 1

1

7

High-throughput

0.437

High

1002055

ARL16
ADP-ribosylation factor-like protein 16

1

6

High-throughput

0.437

High

1061770

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

High-throughput

0.437

High

1244400

NUP43
Nucleoporin Nup43

1

15

High-throughput

0.437

High

1264314

RL26L
Ribosomal protein uL24-like

1

1

High-throughput

0.437

High

66833

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

1133016

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

275454

PR15A
Protein phosphatase 1 regulatory subunit 15A

2

0

High-throughput

0.328

High

887590

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.279

Low

945304

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

1054870

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1129340

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1139349

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

1252845

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

281790

WFS1
Wolframin

1

0

High-throughput

0.268

Low

922281

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

1264309

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024