HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 28877994
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 1121
+	Hs
		1052419 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		279715 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		876384 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		279711 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1052485 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		279704 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05
+	Hs
		1052479 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05
+	Hs
		646301 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1331584 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1299660 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		1349029 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91