HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: Q96D37 (Q96D37)
VAV1 protein (Vav guanine nucleotide exchange factor 1)
Gene: VAV1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned2213
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 790
+	Hs
		279427 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		VAV_HUMAN (12-790): 0: 613: 99.74
+	Hs
		548705 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		VAV_HUMAN (12-790): 0: 613: 99.74
+	Hs
		279728 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ARHG4_HUMAN (82-488): 1.25e-76: 263: 20.09
+	Hs
		279713 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49
+	Hs
		1052486 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49
+	Hs
		279373 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		TRIO_HUMAN (112-624): 3.76e-51: 196: 14.34
+	Hs
		279549 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ARHG7_HUMAN (686-788): 2.09e-15: 82.5: 23.30
+	Dm
		55852 FLOT2_DROME (4-422): 1.58e-141: 413: 42.49		A1ZBA1_DROME (131-445): 4.11e-15: 82: 23.99
+	Hs
		279570 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ITSN1_HUMAN (316-788): 1.05e-10: 67.9: 11.00
+	Hs
		1333795 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49
+	Dm
		993214 Q9VWL0_DROME (2-229): 3.77e-22: 98.8: 16.23		GRAP_DROME (562-787): 4.18e-19: 88.6: 28.63