HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: ARHGC (Q9NZN5)
Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)
Gene: ARHGEF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 1544
+	Hs
		279427 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		VAV_HUMAN (673-1294): 1.01e-96: 334: 15.63
+	Hs
		279667 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		Q96D37_HUMAN (673-1294): 3.02e-97: 334: 15.63
+	Hs
		548705 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		VAV_HUMAN (673-1294): 1.01e-96: 334: 15.63
+	Hs
		279570 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ITSN1_HUMAN (118-1216): 2.17e-82: 302: 13.70
+	Hs
		279549 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ARHG7_HUMAN (656-1340): 4.14e-85: 299: 12.38
+	Hs
		279728 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		ARHG4_HUMAN (506-1220): 1.07e-85: 298: 14.03
+	Hs
		279373 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		TRIO_HUMAN (776-1451): 2.3e-60: 232: 13.39
+	Hs
		1235276 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		NGEF_HUMAN (512-1200): 1.23e-90: 312: 17.07