HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2070 Hs			1 513
+	Mm
		1143426 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		ABI1_MOUSE (1-513): 2.82e-100: 312: 60.04
+	Hs
		1252519 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		ABI2_HUMAN (1-513): 1.82e-91: 290: 100.00
+	Hs
		1021587 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66
+	Hs
		924701 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		924847 GRIP2_HUMAN (3-692): 2.73e-25: 117: 12.67		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		924718 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		1256274 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		SH3R3_HUMAN (370-508): 3.57e-10: 64.7: 20.14
+	Mm
		1113245 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SRBS2_MOUSE (371-509): 7.72e-17: 85.9: 21.53
+	Mm
		1141133 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		GRB2_MOUSE (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		924466 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		1049952 SCRIB_HUMAN (372-771): 2.46e-09: 65.1: 22.66		ARHG6_HUMAN (408-508): 2.64e-22: 102: 29.81
+	Hs
		1020196 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		SH3R3_HUMAN (370-508): 3.57e-10: 64.7: 20.14
+	Mm
		1143413 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SH3R3_MOUSE (393-506): 3.55e-11: 67.8: 22.69
+	Hs
		1049703 SCRIB_HUMAN (372-771): 2.46e-09: 65.1: 22.66		ARHG7_HUMAN (451-508): 2.16e-18: 90.8: 41.38
+	Mm
		88458 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		D3Z656_MOUSE (69-440): 1.05e-09: 63.3: 16.27
+	Mm
		1143433 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SYNJ1_MOUSE (101-491): 6.54e-09: 61: 10.10