HitPredict

Interactor 1: GLRX3 (O76003)
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
Gene: GLRX3

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	25416956, 27107012
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, barcode fusion genetics two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 335 Hs			1 416
+	Hs
		1020660 PDIA5_HUMAN (3-214): 7.7e-37: 140: 17.90		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		495513 THIO_HUMAN (13-116): 4.03e-37: 130: 26.92		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		1067866 PDIA6_HUMAN (1-251): 7.84e-38: 141: 14.78		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		495643 THIO_HUMAN (13-116): 4.03e-37: 130: 26.92		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		532032 PDIA4_HUMAN (1-115): 7.77e-24: 104: 19.67		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98