HitPredict

Interactor 1: KT33A (O76009)
Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I) (Keratin-33A) (K33A)
Gene: KRT33A

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19380743
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 404 Hs			1 896
+	Hs
		280860 KRT37_HUMAN (10-397): 1.18e-149: 433: 60.97		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		359311 K1C14_HUMAN (54-367): 2.36e-143: 417: 61.15		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787899 K1C17_HUMAN (49-367): 1.13e-112: 338: 59.88		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		445014 K1C16_HUMAN (54-369): 2.3e-111: 336: 60.44		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787940 K2C73_HUMAN (9-404): 1.04e-93: 293: 23.87		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		531330 K1C10_HUMAN (52-361): 8.5e-92: 289: 56.01		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787892 KRT83_HUMAN (2-403): 1.83e-92: 288: 26.24		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787893 KRT85_HUMAN (2-403): 2e-90: 283: 26.80		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		213932 KRT86_HUMAN (2-401): 3.99e-90: 282: 26.43		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		280539 KRT34_HUMAN (1-391): 2.51e-90: 279: 90.03		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		318787 K2C75_HUMAN (16-381): 4.29e-87: 276: 26.09		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787979 KRT82_HUMAN (1-401): 7.36e-86: 271: 24.88		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787928 K2C79_HUMAN (9-387): 2.07e-83: 266: 24.54		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787912 K1H2_HUMAN (5-401): 4.47e-81: 257: 67.76		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787911 KT33B_HUMAN (1-404): 1.41e-78: 250: 93.81		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787956 KRT35_HUMAN (2-402): 8.8e-78: 249: 69.08		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		280957 KRT38_HUMAN (7-403): 9.02e-77: 246: 61.31		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		531538 K2C5_HUMAN (19-370): 3.97e-75: 246: 25.99		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		359470 K2C6A_HUMAN (19-391): 3.48e-75: 245: 24.53		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		522624 K1C40_HUMAN (2-387): 1.93e-145: 421: 61.71		MYH7_HUMAN (256-608): 1.36e-14: 80.6: 11.14