HitPredict

Interactor 1: RL1D1 (O76021)
Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1)
Gene: RSL1D1

Interactor 2: RL7A (P62424)
Large ribosomal subunit protein eL8 (60S ribosomal protein L7a) (PLA-X polypeptide) (Surfeit locus protein 3)
Gene: RPL7A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	33961781, 30021884, 24981860, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ribosomal_L1~Ribosomal_L7Ae
Common GO terms	GO:0000470 - maturation of LSU-rRNA GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0016020 - membrane GO:0022625 - cytosolic large ribosomal subunit and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 266
+	Hs
		913464 RL10A_HUMAN (28-264): 7.51e-66: 213: 15.83		RL7A_HUMAN (16-266): 1.89e-119: 344: 100.00
+	Sc
		481111 RL1A_YEAST (29-264): 1.01e-66: 215: 21.34		RL8A_YEAST (7-255): 2.28e-96: 285: 57.60
+	Sc
		481127 RL1A_YEAST (29-264): 1.01e-66: 215: 21.34		RL8B_YEAST (7-255): 9.4e-97: 285: 58.40
+	Sc
		564282 CIC1_YEAST (31-282): 9.75e-39: 146: 21.53		RL8A_YEAST (7-255): 2.28e-96: 285: 57.60
+	Sc
		667170 CIC1_YEAST (31-282): 9.75e-39: 146: 21.53		RL8B_YEAST (7-255): 9.4e-97: 285: 58.40