HitPredict

Interactor 1: CDKL5 (O76039)
Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)
Gene: CDKL5

Interactor 2: CDKL5 (O76039)
Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)
Gene: CDKL5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 16935860, 23602568
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0001764 - neuron migration
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 23 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 960
Hs

1 960
+ Mm
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+ At
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+ Hs
+ Zm
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+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024