HitPredict

Interactor 1: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8

Interactor 2: K2C1B (Q7Z794)
Keratin, type II cytoskeletal 1b (Cytokeratin-1B) (CK-1B) (Keratin-77) (K77) (Type-II keratin Kb39)
Gene: KRT77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35831895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 485 Hs			1 578
+	Hs
		282466 RNF8_HUMAN (1-485): 0: 523: 100.00		K2C1_HUMAN (129-510): 2.95e-163: 481: 68.06
+	Hs
		282504 RNF8_HUMAN (1-485): 0: 523: 100.00		K2C3_HUMAN (136-480): 1.68e-149: 446: 68.01
+	Hs
		282695 RNF8_HUMAN (1-485): 0: 523: 100.00		K2C78_HUMAN (88-523): 1e-117: 360: 50.89
+	Hs
		282510 RNF8_HUMAN (1-485): 0: 523: 100.00		K2C5_HUMAN (1-480): 3.81e-83: 272: 58.23
+	Hs
		282465 RNF8_HUMAN (1-485): 0: 523: 100.00		K2C6B_HUMAN (3-496): 3.98e-82: 269: 58.38
+	Hs
		282457 RNF8_HUMAN (1-485): 0: 523: 100.00		K2C6A_HUMAN (3-496): 5.58e-78: 258: 58.38
+	Hs
		380552 TRI27_HUMAN (392-478): 1.06e-22: 103: 21.11		K2C1_HUMAN (129-510): 2.95e-163: 481: 68.06
+	Hs
		517736 TRI27_HUMAN (392-478): 1.06e-22: 103: 21.11		K2C3_HUMAN (136-480): 1.68e-149: 446: 68.01
+	Hs
		318813 LONF1_HUMAN (243-483): 1.28e-27: 118: 19.26		K2C75_HUMAN (1-566): 2.11e-93: 298: 53.95
+	Hs
		318774 TRI27_HUMAN (392-478): 1.06e-22: 103: 21.11		K2C75_HUMAN (1-566): 2.11e-93: 298: 53.95
+	Hs
		380469 TRI26_HUMAN (391-482): 8.35e-23: 103: 26.32		K2C6B_HUMAN (3-496): 3.98e-82: 269: 58.38
+	Hs
		1089362 LONF1_HUMAN (243-483): 1.28e-27: 118: 19.26		KRT35_HUMAN (48-477): 1.17e-64: 220: 23.20
+	Hs
		536787 TRI27_HUMAN (392-478): 1.06e-22: 103: 21.11		K22O_HUMAN (1-492): 1.25e-67: 232: 54.86