HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	24981860, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 535
+	Hs
		283005 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		282850 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		282815 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		282848 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		943370 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		826784 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		943393 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		573384 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821326 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Dm
		186253 GBLP_DROME (92-339): 5.66e-46: 160: 18.50		Q9W392_DROME (4-535): 0: 568: 70.73
+	Hs
		826807 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		573406 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Sc
		744616 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TCPB_YEAST (9-532): 0: 566: 65.71
+	Sc
		744637 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TCPH_YEAST (1-532): 0: 559: 33.09
+	Hs
		1306704 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Sc
		744617 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TCPG_YEAST (5-528): 0: 537: 28.33
+	Hs
		943508 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		821437 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		821139 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573201 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		TCPA_HUMAN (5-533): 0: 541: 34.30