HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: SEC12 (Q9HCU5)
Guanine nucleotide-exchange factor SEC12 (Prolactin regulatory element-binding protein)
Gene: PREB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 417
+	Hs
		282871 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		WDR5_HUMAN (29-269): 4.37e-37: 139: 9.27
+	Hs
		282843 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		LIS1_HUMAN (251-411): 1.39e-30: 123: 12.43
+	Hs
		1240442 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		POC1A_HUMAN (142-407): 3.87e-60: 202: 15.64
+	Dm
		1358845 WDS_DROME (137-339): 1.46e-47: 165: 20.69		WDS_DROME (9-331): 7.23e-59: 197: 9.76
+	Hs
		863508 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		COPA_HUMAN (11-310): 2.64e-37: 146: 12.35
+	Hs
		903418 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		WDR5_HUMAN (29-269): 4.37e-37: 139: 9.27
+	Hs
		929579 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		RACK1_HUMAN (160-364): 7.77e-19: 88.4: 16.02
+	Sp
		999838 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP11_SCHPO (179-411): 6.13e-43: 160: 12.92
+	Sp
		999842 TUP11_SCHPO (175-339): 1.79e-29: 120: 15.76		TUP12_SCHPO (16-226): 1.28e-37: 145: 15.93
+	Hs
		929603 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		RACK1_HUMAN (160-364): 7.77e-19: 88.4: 16.02
+	Hs
		1103007 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		SMU1_HUMAN (81-222): 4.51e-11: 66.6: 10.14
+	Hs
		863397 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		COPA_HUMAN (11-310): 2.64e-37: 146: 12.35
+	Hs
		903551 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		WDR5_HUMAN (29-269): 4.37e-37: 139: 9.27
+	Hs
		878165 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		WDR5_HUMAN (29-269): 4.37e-37: 139: 9.27
+	Hs
		1346954 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		NLE1_HUMAN (224-391): 1.36e-33: 133: 11.91
+	Sc
		744605 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TAF5_YEAST (11-215): 2.37e-12: 70.6: 8.33
+	Hs
		792949 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		LIS1_HUMAN (251-411): 1.39e-30: 123: 12.43
+	Ca
		483033 TUP1_CANAL (180-338): 4.8e-28: 115: 18.87		TUP1_CANAL (137-394): 1.31e-15: 80.7: 17.15
+	Hs
		929692 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		RACK1_HUMAN (160-364): 7.77e-19: 88.4: 16.02
+	Hs
		196984 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		PRP4_HUMAN (83-225): 2.74e-18: 88.6: 16.55