HitPredict

Interactor 1: CYTF (O76096)
Cystatin-F (Cystatin-7) (Cystatin-like metastasis-associated protein) (CMAP) (Leukocystatin)
Gene: CST7

Interactor 2: CATL1 (P07711)
Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain]
Gene: CTSL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cystatin~Peptidase_C1
Common GO terms	GO:0005615 - extracellular space GO:0005764 - lysosome GO:0005771 - multivesicular body GO:0005794 - Golgi apparatus GO:0006955 - immune response
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 145 Hs			1 333
+	Hs
		344815 CYTC_HUMAN (21-145): 1.16e-47: 152: 32.80		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		344922 CYTN_HUMAN (27-145): 1.08e-47: 152: 31.93		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		245769 CYTC_HUMAN (21-145): 1.16e-47: 152: 32.80		CATL2_HUMAN (1-333): 1.72e-170: 478: 77.25
+	Hs
		245770 CYTN_HUMAN (27-145): 1.08e-47: 152: 31.93		CATL2_HUMAN (1-333): 1.72e-170: 478: 77.25
+	Hs
		429900 CYTM_HUMAN (7-144): 1.46e-35: 121: 29.58		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		245811 CYTM_HUMAN (7-144): 1.46e-35: 121: 29.58		CATL2_HUMAN (1-333): 1.72e-170: 478: 77.25
+	Hs
		345171 KNG1_HUMAN (40-145): 2.32e-10: 59.1: 20.76		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		637215 CYTD_HUMAN (7-145): 1.33e-42: 139: 27.86		CATS_HUMAN (1-333): 5.17e-142: 406: 47.77
+	Hs
		245772 KNG1_HUMAN (40-145): 2.32e-10: 59.1: 20.76		CATL2_HUMAN (1-333): 1.72e-170: 478: 77.25
+	Hs
		344817 CYTC_HUMAN (21-145): 1.16e-47: 152: 32.80		CATH_HUMAN (2-332): 6.44e-128: 370: 37.28
+	Hs
		344926 CYTN_HUMAN (27-145): 1.08e-47: 152: 31.93		CATH_HUMAN (2-332): 6.44e-128: 370: 37.28
+	Hs
		453952 CYTD_HUMAN (7-145): 1.33e-42: 139: 27.86		CATH_HUMAN (2-332): 6.44e-128: 370: 37.28
+	Hs
		345173 KNG1_HUMAN (40-145): 2.32e-10: 59.1: 20.76		CATH_HUMAN (2-332): 6.44e-128: 370: 37.28