HitPredict

Interactor 1: RAB7 (O76742)
Ras-related protein Rab7 (DRab7) (EC 3.6.5.2) (Small monomeric GTPase Rab7) (Small ras-like GTPase)
Gene: RAB7

Interactor 2: MERH (Q24564)
Moesin/ezrin/radixin homolog 2 (Ezrin-moesin-radixin 2) (Merlin) (dMerlin)
Gene: Mer

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24114784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0006897 - endocytosis
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 207 Dm			1 635
+	Hs
		719496 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		MERL_HUMAN (1-635): 4.23e-155: 461: 44.81
+	Hs
		1070407 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		E41L5_HUMAN (3-635): 2.23e-129: 399: 17.16
+	Hs
		914374 RB11A_HUMAN (3-206): 6e-82: 244: 28.30		E41L5_HUMAN (3-635): 2.23e-129: 399: 17.16
+	Hs
		1070391 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		E41LB_HUMAN (3-602): 3.37e-119: 377: 16.05
+	Hs
		1070395 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		E41L1_HUMAN (2-517): 9.73e-115: 365: 21.54
+	Hs
		914356 RB11A_HUMAN (3-206): 6e-82: 244: 28.30		E41L1_HUMAN (2-517): 9.73e-115: 365: 21.54
+	Hs
		204670 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		E41L2_HUMAN (6-522): 6.95e-113: 363: 19.37
+	Hs
		1070467 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		E41L3_HUMAN (7-614): 2.13e-110: 358: 16.25
+	Hs
		505636 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		EPB41_HUMAN (2-567): 2.92e-112: 358: 18.04
+	Hs
		505614 RB11A_HUMAN (3-206): 6e-82: 244: 28.30		EPB41_HUMAN (2-567): 2.92e-112: 358: 18.04
+	Hs
		505600 RAB8A_HUMAN (1-204): 6.46e-82: 243: 30.39		EPB41_HUMAN (2-567): 2.92e-112: 358: 18.04
+	Hs
		1070476 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		FARP1_HUMAN (2-599): 4.97e-108: 351: 17.41