HitPredict

Interactor 1: E2F2 (O77051)
Transcription factor E2F2 (dE2F2) (E2F transcription factor 2) (E2F-like transcription factor E2F2)
Gene: E2F2

Interactor 2: Q9VF04 (Q9VF04)
RE32990p (Retinoblastoma protein homolog RBF2) (Retinoblastoma-family protein 2)
Gene: Rbf2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 15479636, 15456884
Identification Methods affinity chromatography technology, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0031523 - Myb complex
GO:0035189 - Rb-E2F complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 370
Dm

1 783
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024