Protein: ACBD5
Acyl-CoA-binding domain-containing protein 5

Gene: ACBD5
Organism: Homo sapiens
Interactions: 209
UniProt ID: Q5T8D3

Gene Ontology (top 5):
GO:0000062 - fatty-acyl-CoA binding
GO:0000425 - pexophagy
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

333040

VAPB
Vesicle-associated membrane protein-associated protein B/C

7

3

Small-scale

0.745

High

1214593

VAPA
Vesicle-associated membrane protein-associated protein A

6

3

High-throughput

0.732

High

327306

ZFPL1
Zinc finger protein-like 1

4

0

High-throughput

0.661

High

1214599

FBW1B
F-box/WD repeat-containing protein 11

3

4

High-throughput

0.633

High

1214528

ACBD4
Acyl-CoA-binding domain-containing protein 4

1

5

High-throughput

0.618

High

1214575

MYO5C
Unconventional myosin-Vc

2

1

High-throughput

0.611

High

1214583

S38A7
Sodium-coupled neutral amino acid transporter 7

2

1

High-throughput

0.606

High

1156932

CNGA3
Cyclic nucleotide-gated channel alpha-3

3

2

High-throughput

0.604

High

1214514

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.602

High

1214524

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.585

High

611167

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

1

High-throughput

0.584

High

951200

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

960347

STX1B
Syntaxin-1B

2

0

High-throughput

0.580

High

1214526

T229B
Transmembrane protein 229B

2

0

High-throughput

0.580

High

1214513

MAVS
Mitochondrial antiviral-signaling protein

2

0

High-throughput

0.559

High

1214580

TOM22
Mitochondrial import receptor subunit TOM22 homolog

2

0

High-throughput

0.559

High

1214586

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.559

High

396286

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

209285

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

1

High-throughput

0.536

High

1214550

GWL
Serine/threonine-protein kinase greatwall

1

1

High-throughput

0.536

High

522107

BCL2
Apoptosis regulator Bcl-2

1

0

High-throughput

0.513

High

1214507

KLC3
Kinesin light chain 3

1

0

High-throughput

0.513

High

1214574

PRD11
PR domain-containing protein 11

1

0

High-throughput

0.513

High

1214610

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

900857

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.489

High

163962

NDC80
Kinetochore protein NDC80 homolog

1

1

High-throughput

0.479

High

181334

PGRC2
Membrane-associated progesterone receptor component 2

1

1

High-throughput

0.479

High

208516

PJA2
E3 ubiquitin-protein ligase Praja-2

1

2

High-throughput

0.479

High

209030

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.479

High

226795

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

2

High-throughput

0.479

High

291373

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

340155

PCNT
Pericentrin

1

1

High-throughput

0.479

High

450998

LDHB
L-lactate dehydrogenase B chain

1

2

High-throughput

0.479

High

466301

RHOC
Rho-related GTP-binding protein RhoC

1

5

High-throughput

0.479

High

537312

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

543218

UBL4A
Ubiquitin-like protein 4A

1

2

High-throughput

0.479

High

581098

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

588882

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

610367

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

626256

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.479

High

630539

RAB3B
Ras-related protein Rab-3B

1

2

High-throughput

0.479

High

631272

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

731379

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

768386

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

895919

F10A1
Hsc70-interacting protein

1

2

High-throughput

0.479

High

896249

PEX5
Peroxisomal targeting signal 1 receptor

1

1

High-throughput

0.479

High

901295

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

910089

RND2
Rho-related GTP-binding protein RhoN

1

7

High-throughput

0.479

High

913512

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.479

High

921919

COPA
Coatomer subunit alpha

1

2

High-throughput

0.479

High

931540

RD23A
UV excision repair protein RAD23 homolog A

1

6

High-throughput

0.479

High

941914

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

953497

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.479

High

955271

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

962143

RHOA
Transforming protein RhoA

1

5

High-throughput

0.479

High

975078

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

981293

RAB1A
Ras-related protein Rab-1A

1

1

High-throughput

0.479

High

1015507

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

1058459

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

1117327

ARFRP
ADP-ribosylation factor-related protein 1

1

4

High-throughput

0.479

High

1125477

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

1140396

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1200970

ACTBL
Beta-actin-like protein 2

1

1

High-throughput

0.479

High

1214509

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1214515

YTHD3
YTH domain-containing family protein 3

1

2

High-throughput

0.479

High

1214520

VRK2
Serine/threonine-protein kinase VRK2

1

4

High-throughput

0.479

High

1214522

MIRO2
Mitochondrial Rho GTPase 2

1

8

High-throughput

0.479

High

1214527

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1214533

IPO4
Importin-4

1

1

High-throughput

0.479

High

1214537

UBXN4
UBX domain-containing protein 4

1

1

High-throughput

0.479

High

1214540

PEX13
Peroxisomal membrane protein PEX13

1

1

High-throughput

0.479

High

1214544

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

1214554

DNJC1
DnaJ homolog subfamily C member 1

1

2

High-throughput

0.479

High

1214555

RMD2
Regulator of microtubule dynamics protein 2

1

1

High-throughput

0.479

High

1214556

SPAG5
Sperm-associated antigen 5

1

1

High-throughput

0.479

High

1214557

CK5P2
CDK5 regulatory subunit-associated protein 2

1

2

High-throughput

0.479

High

1214558

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

1214562

TTC1
Tetratricopeptide repeat protein 1

1

1

High-throughput

0.479

High

1214564

AKAP9
A-kinase anchor protein 9

1

2

High-throughput

0.479

High

1214569

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1214576

SAR1A
Small COPII coat GTPase SAR1A

1

4

High-throughput

0.479

High

1214577

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

1214579

UBQL4
Ubiquilin-4

1

6

High-throughput

0.479

High

1214585

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.479

High

1214589

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1214595

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.479

High

1214596

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

1214601

UBQL1
Ubiquilin-1

1

3

High-throughput

0.479

High

1214602

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.479

High

1214605

FBW1A
F-box/WD repeat-containing protein 1A

1

4

High-throughput

0.479

High

1214611

KIF3A
Kinesin-like protein KIF3A

1

1

High-throughput

0.479

High

1214613

YTHD2
YTH domain-containing family protein 2

1

2

High-throughput

0.479

High

1214617

ARL5A
ADP-ribosylation factor-like protein 5A

1

3

High-throughput

0.479

High

67772

TBKB1
TANK-binding kinase 1-binding protein 1

1

0

High-throughput

0.458

High

173950

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

176488

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

187983

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.458

High

192261

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.458

High

258925

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

278870

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

337951

CNEP1
CTD nuclear envelope phosphatase 1

1

0

High-throughput

0.458

High

343387

SNP29
Synaptosomal-associated protein 29

1

0

High-throughput

0.458

High

354457

PX11B
Peroxisomal membrane protein 11B

1

0

High-throughput

0.458

High

417489

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418193

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

621484

HXK1
Hexokinase-1

1

0

High-throughput

0.458

High

698750

CALX
Calnexin

1

0

High-throughput

0.458

High

701839

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.458

High

778702

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.458

High

789135

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.458

High

820665

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

828375

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.458

High

837658

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

839775

EPS15
Epidermal growth factor receptor substrate 15

1

0

High-throughput

0.458

High

847558

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

851345

PRS6B
26S proteasome regulatory subunit 6B

1

0

High-throughput

0.458

High

894806

EMD
Emerin

1

0

High-throughput

0.458

High

906066

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.458

High

920024

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

933660

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.458

High

952575

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.458

High

987379

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.458

High

1061242

RHG01
Rho GTPase-activating protein 1

1

0

High-throughput

0.458

High

1124831

FLOT2
Flotillin-2

1

0

High-throughput

0.458

High

1128740

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1134227

IMB1
Importin subunit beta-1

1

0

High-throughput

0.458

High

1214501

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.458

High

1214502

WAC2A
WASH complex subunit 2A

1

0

High-throughput

0.458

High

1214503

THOC7
THO complex subunit 7

1

0

High-throughput

0.458

High

1214505

FAP20
Fanconi anemia core complex-associated protein 20

1

0

High-throughput

0.458

High

1214510

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

0

High-throughput

0.458

High

1214511

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

0

High-throughput

0.458

High

1214516

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.458

High

1214517

TM135
Transmembrane protein 135

1

0

High-throughput

0.458

High

1214518

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

1214519

DGKH
Diacylglycerol kinase eta

1

0

High-throughput

0.458

High

1214521

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.458

High

1214523

CNTRB
Centrobin

1

0

High-throughput

0.458

High

1214532

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.458

High

1214534

SYNE2
Nesprin-2

1

0

High-throughput

0.458

High

1214535

TM131
Transmembrane protein 131

1

0

High-throughput

0.458

High

1214536

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.458

High

1214539

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1214541

MARC2
Mitochondrial amidoxime reducing component 2

1

0

High-throughput

0.458

High

1214542

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.458

High

1214547

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.458

High

1214551

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1214553

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

0

High-throughput

0.458

High

1214559

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1214560

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

1214561

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.458

High

1214563

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.458

High

1214565

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1214570

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1214571

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.458

High

1214578

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1214581

DIAP3
Protein diaphanous homolog 3

1

0

High-throughput

0.458

High

1214582

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1214584

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1214587

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

1214591

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1214592

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.458

High

1214594

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

1214597

TRPS1
Zinc finger transcription factor Trps1

1

0

High-throughput

0.458

High

1214598

APC4
Anaphase-promoting complex subunit 4

1

0

High-throughput

0.458

High

1214604

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.458

High

1214609

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1214614

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.458

High

1214615

PEX16
Peroxisomal membrane protein PEX16

1

0

High-throughput

0.458

High

1214616

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.458

High

1007441

S35B1
Solute carrier family 35 member B1

1

7

High-throughput

0.445

High

1131546

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.445

High

1175867

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

5

High-throughput

0.445

High

1214504

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.445

High

1214529

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

1

High-throughput

0.445

High

1214530

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

8

High-throughput

0.445

High

1214573

S35C2
Solute carrier family 35 member C2

1

5

High-throughput

0.445

High

1214508

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

1

High-throughput

0.437

High

1214525

ARL10
ADP-ribosylation factor-like protein 10

1

3

High-throughput

0.437

High

1214546

FAF2
FAS-associated factor 2

1

1

High-throughput

0.437

High

1214566

NUP58
Nucleoporin p58/p45

1

1

High-throughput

0.437

High

1214567

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.437

High

1214600

ALK
ALK tyrosine kinase receptor

1

3

High-throughput

0.437

High

1214603

SNX7
Sorting nexin-7

1

1

High-throughput

0.437

High

1214608

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

1

High-throughput

0.437

High

1214612

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.437

High

765608

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

841191

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

1214506

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.426

High

1214548

SAAL1
Protein SAAL1

1

0

High-throughput

0.426

High

1214607

S27A5
Long-chain fatty acid transport protein 5

1

1

High-throughput

0.407

High

1126104

GRM2
Metabotropic glutamate receptor 2

2

0

High-throughput

0.316

High

1214543

S2546
Mitochondrial outer membrane protein SLC25A46

2

0

High-throughput

0.305

High

124371

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

1054185

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

0

High-throughput

0.249

Low

1111565

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1147607

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

1193584

CE022
UPF0489 protein C5orf22

1

0

High-throughput

0.249

Low

1214512

MIGA2
Mitoguardin 2

1

0

High-throughput

0.249

Low

1214531

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

1214538

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

1214545

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.249

Low

1214549

CFA36
Cilia- and flagella-associated protein 36

1

0

High-throughput

0.249

Low

1214552

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low

1214568

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1214572

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

1214588

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.249

Low

1214590

GGA3
ADP-ribosylation factor-binding protein GGA3

1

0

High-throughput

0.249

Low

1214606

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025