HitPredict

Interactor 1: A0A0G2JIW1 (A0A0G2JIW1)
Heat shock 70 kDa protein 1B
Gene: HSPA1B

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 2527
+	Hs
		483766 HS71A_HUMAN (2-642): 0: 982: 100.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130801 V9HW22_HUMAN (2-614): 0: 978: 86.62		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		504206 HSP7C_HUMAN (2-614): 0: 978: 86.62		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		564025 HSP76_HUMAN (7-642): 0: 983: 82.55		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74
+	Hs
		503596 HSP7C_HUMAN (2-614): 0: 978: 86.62		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74
+	Hs
		504171 HSP7C_HUMAN (2-614): 0: 978: 86.62		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		201242 HS71L_HUMAN (3-642): 0: 989: 89.06		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201190 HSP7C_HUMAN (2-614): 0: 978: 86.62		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201280 HSP72_HUMAN (3-642): 0: 959: 83.33		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	At
		612329 HS701_ARATH (1-642): 0: 966: 74.88		BRL2_ARATH (1470-1771): 1.68e-09: 65.8: 10.33