Protein: AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4) (HSP-975) (HSVI-binding protein) (SR-15) (SRp25) (SR-25) (Splicing factor SRrp37)

Gene: AR6P4, ARL6IP4
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q66PJ3

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1226795

SRPK1
SRSF protein kinase 1

4

1

High-throughput

0.702

High

1226765

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

4

1

High-throughput

0.695

High

1006472

SRPK2
SRSF protein kinase 2

3

1

High-throughput

0.667

High

1006142

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

3

2

High-throughput

0.667

High

1226768

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

0

High-throughput

0.638

High

1226769

ZC3HE
Zinc finger CCCH domain-containing protein 14

3

0

High-throughput

0.638

High

1226791

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

3

0

High-throughput

0.638

High

1226817

CCDC9
Coiled-coil domain-containing protein 9

3

0

High-throughput

0.638

High

1226807

RNF41
E3 ubiquitin-protein ligase NRDP1

3

2

Small-scale

0.611

High

625441

CSK22
Casein kinase II subunit alpha'

2

1

High-throughput

0.611

High

871950

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

2

High-throughput

0.609

High

1226775

GPAM1
GPALPP motifs-containing protein 1

3

1

High-throughput

0.609

High

1226786

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

3

2

High-throughput

0.609

High

987700

GRB2
Growth factor receptor-bound protein 2

2

0

High-throughput

0.601

High

329762

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

2

0

High-throughput

0.585

High

1198569

NCBP3
Nuclear cap-binding protein subunit 3

2

0

High-throughput

0.585

High

980840

H2B1C
Histone H2B type 1-C/E/F/G/I

2

3

High-throughput

0.584

High

563904

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

1226782

NUP43
Nucleoporin Nup43

2

0

High-throughput

0.559

High

997781

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.550

High

1051483

SRS11
Serine/arginine-rich splicing factor 11

1

0

High-throughput

0.549

High

1126949

RBM39
RNA-binding protein 39

1

0

High-throughput

0.549

High

1226811

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.549

High

1226793

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.541

High

1226802

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.541

High

370697

FOS
Protein c-Fos

1

0

High-throughput

0.537

High

577448

ETS1
Protein C-ets-1

1

0

High-throughput

0.537

High

280663

PR40A
Pre-mRNA-processing factor 40 homolog A

1

2

High-throughput

0.515

High

1226819

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.513

High

159695

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.513

High

478082

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

480183

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

542063

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

574317

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

1065236

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1160161

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

436899

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.493

High

910551

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.493

High

930932

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

937029

CASP6
Caspase-6

1

0

High-throughput

0.493

High

966455

1433G
14-3-3 protein gamma

1

0

High-throughput

0.493

High

981538

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

986489

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.493

High

1139732

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.493

High

1226785

LMO3
LIM domain only protein 3

1

0

High-throughput

0.493

High

1226790

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

67834

SRRM4
Serine/arginine repetitive matrix protein 4

1

1

High-throughput

0.481

High

1208158

NKAPL
NKAP-like protein

1

2

High-throughput

0.481

High

1226787

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

1

High-throughput

0.481

High

1226799

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.481

High

331046

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

372276

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406274

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

606850

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

1035695

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1051008

FAK1
Focal adhesion kinase 1

1

1

Small-scale

0.479

High

1226776

H2B3B
Histone H2B type 3-B

1

3

High-throughput

0.479

High

1226792

H2B1H
Histone H2B type 1-H

1

3

High-throughput

0.479

High

1226798

H2B1L
Histone H2B type 1-L

1

3

High-throughput

0.479

High

172933

XPO1
Exportin-1

1

0

High-throughput

0.458

High

247957

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

335141

ARI2
E3 ubiquitin-protein ligase ARIH2

1

0

High-throughput

0.458

High

400985

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

414014

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

472813

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

487420

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

583315

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

830909

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

854870

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.458

High

937781

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

970649

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

979817

H4
Histone H4

1

0

High-throughput

0.458

High

1016937

H33
Histone H3.3

1

0

High-throughput

0.458

High

1045395

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1138308

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1140411

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1141169

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.458

High

1202191

DCAF6
DDB1- and CUL4-associated factor 6

1

0

High-throughput

0.458

High

1213449

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

1226772

DET1
DET1 homolog

1

0

High-throughput

0.458

High

1226773

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1226783

COP1
E3 ubiquitin-protein ligase COP1

1

0

High-throughput

0.458

High

1226784

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1226789

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1226796

NECD
Necdin

1

0

High-throughput

0.458

High

1226803

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1226804

RNF38
E3 ubiquitin-protein ligase RNF38

1

0

Small-scale

0.458

High

1226806

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1226808

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1226810

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1226812

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1226771

NKAP1
Uncharacterized protein NKAPD1

1

1

High-throughput

0.439

High

1226800

AP1M1
AP-1 complex subunit mu-1

1

1

High-throughput

0.439

High

1226809

KRCC1
Lysine-rich coiled-coil protein 1

1

1

High-throughput

0.439

High

1226766

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1226770

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

765617

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

977276

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.426

High

1226777

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1226781

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

886945

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

295339

EIF3J
Eukaryotic translation initiation factor 3 subunit J

3

0

High-throughput

0.347

High

1226788

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

0

High-throughput

0.331

High

1041449

ACY1
Aminoacylase-1

2

0

High-throughput

0.318

High

1226815

FBW1A
F-box/WD repeat-containing protein 1A

2

0

High-throughput

0.305

High

1106481

GAB1
GRB2-associated-binding protein 1

2

0

High-throughput

0.298

High

1175804

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

1226767

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low

1226801

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.279

Low

282595

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.268

Low

283882

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.268

Low

441542

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

562129

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

603294

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.268

Low

650225

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

719946

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.268

Low

925551

MOT1
Monocarboxylate transporter 1

1

0

High-throughput

0.268

Low

1081536

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

1133881

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1210655

Q5SUL5
HLA class I histocompatibility antigen A alpha chain

1

0

High-throughput

0.268

Low

1226814

UBQL1
Ubiquilin-1

1

0

High-throughput

0.268

Low

1226818

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1226805

ARL6
ADP-ribosylation factor-like protein 6

1

0

Small-scale

0.251

Low

136914

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.249

Low

472318

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

879183

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

903955

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.249

Low

1226774

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.249

Low

1226778

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.249

Low

1226797

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.249

Low

1226813

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1226816

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low

839033

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.232

Low

1210872

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.232

Low

1226779

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

1226780

DIK2A
Divergent protein kinase domain 2A

1

0

Small-scale

0.232

Low

1226794

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025