Interactor 1: IKKB (O88351)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: Ikbkb

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21949249
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IKBKB_SDD~Pkinase, Pkinase~Pkinase, Pkinase~TBK1_CCD1, Pkinase~TBK1_ULD
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0018105 - peptidyl-serine phosphorylation
GO:0019903 - protein phosphatase binding
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 757
Mm

1 729
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Gm
+ At
+ At
+ At
+ Zm
+ At

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Last updated: 15 Jul 2024