Protein: SEH1
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)

Gene: SEH1, SEH1L
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q96EE3

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005198 - structural molecule activity
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1338891

NUP43
Nucleoporin Nup43

9

18

Small-scale

0.972

High

938263

SEC13
Protein SEC13 homolog

5

16

Small-scale

0.929

High

1388902

NUP85
Nuclear pore complex protein Nup85

5

5

Small-scale

0.918

High

1388895

WDR24
GATOR2 complex protein WDR24

4

19

Small-scale

0.881

High

1245319

WDR59
GATOR2 complex protein WDR59

3

18

Small-scale

0.847

High

1388911

MIOS
GATOR2 complex protein MIOS

2

20

Small-scale

0.789

High

945293

NU107
Nuclear pore complex protein Nup107

5

6

Small-scale

0.709

High

224151

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

4

High-throughput

0.691

High

876114

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.691

High

882083

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.691

High

899522

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.691

High

916022

NUP98
Nuclear pore complex protein Nup98-Nup96

1

20

High-throughput

0.691

High

1126739

BECN1
Beclin-1

1

1

High-throughput

0.691

High

1339088

NUP37
Nucleoporin Nup37

1

16

High-throughput

0.691

High

1388900

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.691

High

1388901

NDC1
Nucleoporin NDC1

1

1

High-throughput

0.691

High

1356921

NU133
Nuclear pore complex protein Nup133

3

4

Small-scale

0.667

High

993704

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.656

High

1210361

NU188
Nucleoporin NUP188

1

0

High-throughput

0.656

High

384713

CRYAB
Alpha-crystallin B chain

3

8

High-throughput

0.650

High

1144787

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

0

High-throughput

0.622

High

1111186

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.618

High

1007756

RAE1L
mRNA export factor RAE1

1

19

High-throughput

0.618

High

1227236

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.618

High

1356179

NPRL2
GATOR1 complex protein NPRL2

1

6

Small-scale

0.618

High

1388903

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

16

High-throughput

0.618

High

1388899

NUP88
Nuclear pore complex protein Nup88

2

1

High-throughput

0.611

High

957472

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.586

High

372808

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.585

High

242555

PRKN
E3 ubiquitin-protein ligase parkin

2

14

High-throughput

0.584

High

1153083

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

2

0

High-throughput

0.576

High

343006

HERC2
E3 ubiquitin-protein ligase HERC2

1

5

High-throughput

0.575

High

1388897

NELL2
Protein kinase C-binding protein NELL2

2

9

High-throughput

0.574

High

1335506

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

2

0

High-throughput

0.559

High

315872

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.553

High

980122

H4
Histone H4

1

3

High-throughput

0.553

High

1255014

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.553

High

1388905

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.553

High

1388916

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.553

High

1371946

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.541

High

391817

OSTCN
Osteocalcin

1

1

High-throughput

0.536

High

775587

NU214
Nuclear pore complex protein Nup214

1

20

High-throughput

0.536

High

854710

RAGP1
Ran GTPase-activating protein 1

1

4

High-throughput

0.536

High

890385

NU153
Nuclear pore complex protein Nup153

1

20

High-throughput

0.536

High

890557

RBP2
E3 SUMO-protein ligase RanBP2

1

3

High-throughput

0.536

High

991395

SUMO1
Small ubiquitin-related modifier 1

1

1

High-throughput

0.536

High

1085265

NU160
Nuclear pore complex protein Nup160

1

3

High-throughput

0.536

High

1134324

IMB1
Importin subunit beta-1

1

7

High-throughput

0.536

High

1199349

GLE1
mRNA export factor GLE1

1

11

High-throughput

0.536

High

1211534

SZT2
KICSTOR complex protein SZT2

1

1

Small-scale

0.536

High

1238667

TM214
Transmembrane protein 214

1

1

High-throughput

0.536

High

1323433

NUP93
Nuclear pore complex protein Nup93

1

4

High-throughput

0.536

High

1339129

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.536

High

1365878

NU205
Nuclear pore complex protein Nup205

1

3

High-throughput

0.536

High

1370281

CSN5
COP9 signalosome complex subunit 5

1

9

High-throughput

0.536

High

1388906

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1388909

AAAS
Aladin

1

18

High-throughput

0.536

High

1388913

NXF1
Nuclear RNA export factor 1

1

2

High-throughput

0.536

High

1388917

PKHM1
Pleckstrin homology domain-containing family M member 1

1

3

Small-scale

0.536

High

589386

RFA2
Replication protein A 32 kDa subunit

2

4

High-throughput

0.533

High

696186

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

4

High-throughput

0.533

High

768865

RFA3
Replication protein A 14 kDa subunit

2

4

High-throughput

0.533

High

831222

CCNF
Cyclin-F

1

6

High-throughput

0.515

High

1293558

F131B
Protein FAM131B

1

0

High-throughput

0.513

High

1352921

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.513

High

1388896

TM209
Transmembrane protein 209

1

0

High-throughput

0.513

High

384514

CRYAA
Alpha-crystallin A chain

1

8

High-throughput

0.501

High

967906

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

Small-scale

0.501

High

295961

PPR37
Protein phosphatase 1 regulatory subunit 37

1

2

High-throughput

0.489

High

1228696

C102B
Coiled-coil domain-containing protein 102B

1

6

High-throughput

0.489

High

1388898

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.489

High

1388910

NRBP2
Nuclear receptor-binding protein 2

1

7

High-throughput

0.489

High

291483

NU155
Nuclear pore complex protein Nup155

1

5

High-throughput

0.479

High

331226

KI20A
Kinesin-like protein KIF20A

1

10

High-throughput

0.479

High

386077

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

10

High-throughput

0.479

High

537692

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.479

High

540618

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

Small-scale

0.479

High

541633

FGFR1
Fibroblast growth factor receptor 1

1

9

High-throughput

0.479

High

679382

DNJB2
DnaJ homolog subfamily B member 2

1

7

High-throughput

0.479

High

901477

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

905017

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

920180

PLK1
Serine/threonine-protein kinase PLK1

1

8

High-throughput

0.479

High

927096

ATX3
Ataxin-3

1

1

Small-scale

0.479

High

984234

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

18

High-throughput

0.479

High

1108028

SQSTM
Sequestosome-1

1

5

High-throughput

0.479

High

1113958

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1161597

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

1334757

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

1340499

DNJB8
DnaJ homolog subfamily B member 8

1

8

High-throughput

0.479

High

1388893

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1388907

NMRL1
NmrA-like family domain-containing protein 1

1

3

High-throughput

0.479

High

1388914

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1388915

FAF1
FAS-associated factor 1

1

5

High-throughput

0.479

High

582609

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.458

High

1385599

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1388918

KPTN
KICSTOR complex protein kaptin

1

0

Small-scale

0.458

High

68023

P121C
Nuclear envelope pore membrane protein POM 121C

1

20

High-throughput

0.445

High

96922

E9PF10
Nucleoporin 155

1

5

High-throughput

0.445

High

171552

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

530206

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High

626328

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

10

High-throughput

0.445

High

983551

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

17

High-throughput

0.445

High

1388894

NUDC1
NudC domain-containing protein 1

1

2

High-throughput

0.445

High

76142

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

20

High-throughput

0.437

High

248036

NUPR1
Nuclear protein 1

1

3

High-throughput

0.437

High

294159

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

341643

EYA4
Protein phosphatase EYA4

1

18

High-throughput

0.437

High

407879

SEMG1
Semenogelin-1

1

1

High-throughput

0.437

High

455658

KLK3
Prostate-specific antigen

1

3

High-throughput

0.437

High

641229

FGFR2
Fibroblast growth factor receptor 2

1

10

High-throughput

0.437

High

648624

FGFR4
Fibroblast growth factor receptor 4

1

10

High-throughput

0.437

High

650344

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.437

High

671839

ZA2G
Zinc-alpha-2-glycoprotein

1

3

High-throughput

0.437

High

851798

NKX21
Homeobox protein Nkx-2.1

1

6

High-throughput

0.437

High

965154

WDR5
WD repeat-containing protein 5

1

18

High-throughput

0.437

High

1036585

SEMG2
Semenogelin-2

1

1

High-throughput

0.437

High

1224884

TENS2
Tensin-2

1

7

High-throughput

0.437

High

1329803

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.437

High

1352681

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.437

High

1359385

DNJB3
DnaJ homolog subfamily B member 3

1

8

High-throughput

0.437

High

1388908

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

2

High-throughput

0.437

High

1388912

HECW2
E3 ubiquitin-protein ligase HECW2

1

3

High-throughput

0.437

High

664895

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.426

High

1314357

SLX4
Structure-specific endonuclease subunit SLX4

1

10

High-throughput

0.407

High

887108

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.373

High

1388904

PDGFD
Platelet-derived growth factor D

3

0

High-throughput

0.345

High

480502

GROA
Growth-regulated alpha protein

2

0

High-throughput

0.313

High

1155024

ADIPO
Adiponectin

2

0

High-throughput

0.313

High

168306

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.279

Low

192122

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.279

Low

1315504

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

377684

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

465857

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.249

Low

1352590

SAP25
Histone deacetylase complex subunit SAP25

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025