HitPredict

Interactor 1: NEMO (O88522)
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: Ikbkg

Interactor 2: NEMO (O88522)
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: Ikbkg

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 19830703, 24240172, 18216269, 20211142
Identification Methods affinity chromatography technology, cosedimentation in solution, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CC2-LZ~CC2-LZ, NEMO~NEMO
Common GO terms GO:0001782 - B cell homeostasis
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
GO:0007249 - canonical NF-kappaB signal transduction
and 18 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 412
Mm

1 412
+ Bt
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs

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Last updated: 15 Jul 2024