HitPredict

Interactor 1: NEMO (O88522)
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: Ikbkg

Interactor 2: RB6I2 (Q99MI1)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (CAZ-associated structural protein 2) (CAST2) (Rab6-interacting protein 2)
Gene: Erc1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21811235
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Mm			1 1120
+	Hs
		1216175 NEMO_HUMAN (1-412): 1.2e-68: 224: 86.40		RB6I2_HUMAN (1-1120): 1.67e-86: 305: 96.43
+	Hs
		1216165 ITSN2_HUMAN (2-383): 8.92e-25: 109: 13.69		RB6I2_HUMAN (1-1120): 1.67e-86: 305: 96.43
+	Hs
		725092 NEMO_HUMAN (1-412): 1.2e-68: 224: 86.40		MYH9_HUMAN (439-1120): 2.19e-30: 132: 12.57
+	Hs
		725276 NEMO_HUMAN (1-412): 1.2e-68: 224: 86.40		MYH10_HUMAN (2-659): 3.06e-28: 126: 11.18
+	Hs
		528386 OPTN_HUMAN (67-411): 1.74e-36: 142: 26.40		MYH6_HUMAN (322-1118): 9.16e-36: 150: 12.71
+	Hs
		724957 OPTN_HUMAN (67-411): 1.74e-36: 142: 26.40		MYH9_HUMAN (439-1120): 2.19e-30: 132: 12.57
+	Hs
		724943 MY18A_HUMAN (33-384): 1.23e-29: 123: 17.26		MYH9_HUMAN (439-1120): 2.19e-30: 132: 12.57
+	Hs
		725065 MYO5B_HUMAN (61-387): 7.82e-29: 121: 15.54		MYH9_HUMAN (439-1120): 2.19e-30: 132: 12.57
+	Hs
		1078856 ITSN1_HUMAN (12-368): 5e-36: 142: 15.31		MYH14_HUMAN (425-1120): 2.18e-23: 109: 14.43
+	Hs
		725013 TARA_HUMAN (30-279): 7.09e-27: 115: 19.47		MYH9_HUMAN (439-1120): 2.19e-30: 132: 12.57
+	Hs
		502925 OPTN_HUMAN (67-411): 1.74e-36: 142: 26.40		MYH3_HUMAN (3-494): 2.5e-15: 83.7: 8.28
+	Hs
		254506 OPTN_HUMAN (67-411): 1.74e-36: 142: 26.40		ROCK2_HUMAN (347-986): 1.03e-09: 65.1: 22.04
+	Hs
		725035 MYO5C_HUMAN (112-363): 6.68e-09: 60: 16.80		MYH9_HUMAN (439-1120): 2.19e-30: 132: 12.57
+	Hs
		1268060 MY18A_HUMAN (33-384): 1.23e-29: 123: 17.26		MY18A_HUMAN (207-863): 7.07e-09: 62.4: 19.02
+	Hs
		1268114 MYO5B_HUMAN (61-387): 7.82e-29: 121: 15.54		MY18A_HUMAN (207-863): 7.07e-09: 62.4: 19.02
+	Hs
		1268090 TARA_HUMAN (30-279): 7.09e-27: 115: 19.47		MY18A_HUMAN (207-863): 7.07e-09: 62.4: 19.02
+	Hs
		1268126 MRCKB_HUMAN (26-348): 2.01e-25: 111: 14.93		MY18A_HUMAN (207-863): 7.07e-09: 62.4: 19.02
+	Hs
		1137898 MRCKA_HUMAN (79-385): 2.65e-19: 92.8: 15.05		KI20B_HUMAN (331-911): 5.32e-10: 66.2: 20.65
+	Ce
		136548 MRCK_CAEEL (23-361): 4.63e-12: 70: 13.45		O44490_CAEEL (161-868): 2.19e-09: 63.9: 19.83
+	Hs
		1268099 MYO5C_HUMAN (112-363): 6.68e-09: 60: 16.80		MY18A_HUMAN (207-863): 7.07e-09: 62.4: 19.02