HitPredict

Interactor 1: BECN1 (O88597)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: PI3R4 (Q8VD65)
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1)
Gene: Pik3r4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 19270693, 24849286, 23332761
Identification Methods tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005776 - autophagosome
GO:0006622 - protein targeting to lysosome
GO:0010506 - regulation of autophagy
GO:0016236 - macroautophagy
GO:0016241 - regulation of macroautophagy
and 10 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 448
Mm

1 1358
+ Hs
+ Sc
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024