HitPredict

Interactor 1: HCN1 (O88704)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2)
Gene: HCN1

Interactor 2: DSCAM (Q9ERC8)
Cell adhesion molecule DSCAM (Down syndrome cell adhesion molecule homolog)
Gene: DSCAM

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030424 - axon GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 910 Mm			1 2013
+	Hs
		240072 HCN1_HUMAN (1-910): 0: 666: 90.24		SDK1_HUMAN (509-2007): 2.09e-105: 379: 13.33
+	Hs
		239967 HCN1_HUMAN (1-910): 0: 666: 90.24		CNTN1_HUMAN (1-665): 5.39e-38: 158: 13.62
+	Hs
		239737 HCN1_HUMAN (1-910): 0: 666: 90.24		PTPRF_HUMAN (17-987): 3.27e-29: 130: 13.82
+	Hs
		239813 HCN1_HUMAN (1-910): 0: 666: 90.24		L1CAM_HUMAN (1081-1968): 2.32e-27: 124: 11.91
+	Hs
		240124 HCN1_HUMAN (1-910): 0: 666: 90.24		NEO1_HUMAN (8-305): 2.4e-12: 74.7: 11.22
+	Hs
		240114 HCN1_HUMAN (1-910): 0: 666: 90.24		TITIN_HUMAN (958-1290): 1.03e-10: 69.8: 9.54
+	Mm
		57583 KCNH2_MOUSE (2-857): 1.19e-154: 486: 18.14		TITIN_MOUSE (1184-1396): 7.76e-17: 89.9: 18.31