HitPredict

Interactor 1: SH21A (O88890)
SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: Sh2d1a

Interactor 2: PHAG1 (Q3U1F9)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26512138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	GO:0002250 - adaptive immune response
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 126 Mm			1 429
+	Mm
		411925 LCK_MOUSE (1-124): 1.07e-40: 142: 20.77		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		639443 LYN_MOUSE (1-124): 3.94e-39: 138: 19.23		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		1112232 SHIP1_MOUSE (5-126): 1.89e-37: 135: 36.89		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		763390 FYN_MOUSE (1-124): 5.46e-37: 133: 18.66		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		782848 CSK_MOUSE (1-124): 2.95e-35: 127: 25.00		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Mm
		1112191 GRB2_MOUSE (1-114): 1.31e-33: 118: 24.56		PHAG1_MOUSE (1-429): 0: 785: 100.00
+	Rn
		693647 CSK_RAT (1-124): 2.95e-35: 127: 25.00		PHAG1_RAT (1-429): 0: 764: 89.51
+	Hs
		411873 LCK_HUMAN (1-124): 8.45e-41: 143: 20.77		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		434038 LYN_HUMAN (1-124): 3.9e-39: 138: 19.23		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		412375 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		523175 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		789135 FRK_HUMAN (1-124): 5.62e-37: 132: 23.08		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		782829 CSK_HUMAN (1-124): 2.89e-35: 127: 25.00		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		337571 ABL1_HUMAN (1-124): 5.64e-34: 125: 25.00		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		924899 GRB2_HUMAN (1-114): 8.68e-34: 118: 24.56		PHAG1_HUMAN (1-429): 0: 705: 78.21
+	Hs
		796661 KSYK_HUMAN (6-111): 1.15e-15: 73.5: 25.23		PHAG1_HUMAN (1-429): 0: 705: 78.21