Interactor 1: P63 (O88898)
Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L)
Gene: Tp63

Interactor 2: P63 (O88898)
Tumor protein 63 (p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L)
Gene: Tp63

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.822

The method score is based on:

Property Details
Experiments 21335238, 22575646
Identification Methods molecular sieving, light scattering, cross-linking study, mass spectrometry studies of complexes, cosedimentation in solution, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains P53~P53, P53~P53_tetramer, P53_tetramer~P53_tetramer, SAM_2~SAM_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 76 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 680
Mm

1 680
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Dr
+ Dr
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024