HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: ROR1 (Q01973)
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)
Gene: ROR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 937
+	Hs
		64695 RHG32_HUMAN (1-2087): 0: 1424: 100.00		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		64625 RHG32_HUMAN (1-2087): 0: 1424: 100.00		MUSK_HUMAN (30-758): 2.24e-169: 517: 26.91
+	Hs
		64712 RHG32_HUMAN (1-2087): 0: 1424: 100.00		NTRK2_HUMAN (435-754): 9.13e-115: 372: 41.75
+	Mm
		546314 RHG32_MOUSE (1-2087): 0: 1404: 87.28		NTRK2_MOUSE (435-754): 2.05e-114: 372: 41.75
+	Hs
		64640 RHG32_HUMAN (1-2087): 0: 1424: 100.00		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		64711 RHG32_HUMAN (1-2087): 0: 1424: 100.00		NTRK3_HUMAN (438-743): 2.52e-67: 243: 40.50
+	Hs
		64660 RHG32_HUMAN (1-2087): 0: 1424: 100.00		EPHB2_HUMAN (465-742): 2.62e-53: 204: 39.16
+	Hs
		253341 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		253307 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		508041 RHG29_HUMAN (134-911): 5.44e-66: 249: 11.78		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		507972 ABR_HUMAN (350-569): 2.79e-66: 245: 32.89		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		507962 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		607950 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		FGFR4_HUMAN (445-766): 3.1e-115: 373: 33.83
+	Hs
		384788 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		253302 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		384998 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		385580 RHG35_HUMAN (9-584): 3.79e-67: 254: 16.47		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		993022 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		NTRK3_HUMAN (438-743): 2.52e-67: 243: 40.50
+	Hs
		253317 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		EPHB2_HUMAN (465-742): 2.62e-53: 204: 39.16
+	Hs
		435622 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		IGF1R_HUMAN (467-742): 3.41e-54: 207: 39.71