HitPredict

Interactor 1: UBA1 (O94609)
Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45) (Poly(A)+ RNA transport protein 3)
Gene: ptr3

Interactor 2: UBC15 (Q9Y818)
Ubiquitin-conjugating enzyme E2 15 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 15) (Ubiquitin carrier protein 15) (Ubiquitin-protein ligase 15)
Gene: UBC15

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.710

Property	Details
Experiments	28162934
Identification Methods	enzymatic study, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1012 Sp			1 167
+	Hs
		607190 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D4_HUMAN (6-164): 7.01e-72: 214: 31.45
+	Hs
		607046 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2G1_HUMAN (1-165): 3.92e-71: 213: 66.27
+	Hs
		607026 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D1_HUMAN (6-164): 8.24e-71: 212: 32.08
+	Hs
		607050 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D2_HUMAN (6-164): 9.2e-71: 212: 30.82
+	Hs
		607099 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2R2_HUMAN (4-160): 8.18e-69: 210: 47.24
+	Oc
		1100193 UBA1_RABIT (2-1012): 0: 1211: 53.12		UB2R2_RABIT (4-160): 8.18e-69: 210: 47.24
+	Hs
		607039 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D3_HUMAN (6-164): 1.12e-69: 209: 30.82
+	Hs
		607136 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E2_HUMAN (4-164): 2.04e-67: 205: 31.06
+	Hs
		607038 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2G2_HUMAN (1-163): 1.39e-66: 202: 52.15
+	Sp
		293848 UBA1_SCHPO (1-1012): 0: 1193: 100.00		UBC4_SCHPO (6-164): 7.45e-70: 209: 30.82
+	Sp
		116506 UBA1_SCHPO (1-1012): 0: 1193: 100.00		UBC7_SCHPO (1-162): 2.15e-69: 208: 51.24
+	Hs
		607022 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2R1_HUMAN (1-147): 3.79e-46: 152: 51.70
+	Sc
		549788 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC4_YEAST (1-164): 2.02e-70: 210: 29.88
+	Sc
		608719 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC7_YEAST (3-163): 2.37e-66: 201: 52.17
+	Hs
		607023 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2A_HUMAN (3-163): 1.25e-30: 110: 36.03
+	Hs
		607054 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2B_HUMAN (3-163): 7.77e-30: 108: 35.40
+	Sp
		293847 UBA1_SCHPO (1-1012): 0: 1193: 100.00		UBC2_SCHPO (1-165): 5.53e-35: 121: 40.61
+	Sc
		539443 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC3_YEAST (3-167): 2.96e-41: 141: 45.83
+	Hs
		48104 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D1_HUMAN (6-164): 8.24e-71: 212: 32.08
+	Sc
		410211 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC2_YEAST (3-165): 1e-30: 110: 36.81