HitPredict

Interactor 1: SEM1 (O94742)
26S proteasome complex subunit SEM1
Gene: SEM1

Interactor 2: SAC3 (P46674)
Nuclear mRNA export protein SAC3 (Leucine permease transcriptional regulator)
Gene: SAC3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	22343721, 27422657, 19061648, 19289793, 37968396, 23643786
Identification Methods	pull down, tandem affinity purification, biochemical, affinity chromatography technology, x-ray crystallography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DSS1_SEM1~SAC3_GANP
Common GO terms	GO:0006406 - mRNA export from nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060090 - molecular adaptor activity GO:0070390 - transcription export complex 2
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 89 Sc			1 1301
+	Sc
		294166 SEM1_YEAST (1-89): 6.2e-39: 126: 100.00		THP3_YEAST (31-538): 2.83e-72: 251: 14.12