HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006260 - DNA replication
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 425
+	Hs
		294989 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5B_HUMAN (1-254): 1.38e-58: 196: 14.83
+	Hs
		294756 RECQ4_HUMAN (1-1208): 0: 794: 100.00		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		294680 RECQ4_HUMAN (1-1208): 0: 794: 100.00		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		294619 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		295186 RECQ4_HUMAN (1-1208): 0: 794: 100.00		GRWD1_HUMAN (307-404): 4.14e-14: 75.7: 23.47
+	Hs
		867652 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15
+	Hs
		1333547 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15
+	Hs
		295566 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15
+	Hs
		1271679 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15
+	Hs
		181721 DDX3Y_HUMAN (305-843): 2.04e-126: 405: 15.09		POC1A_HUMAN (2-184): 3.16e-24: 105: 10.58
+	Hs
		133956 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		903507 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		903410 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		571382 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		903327 DDX46_HUMAN (244-1038): 7.91e-111: 374: 12.44		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61