HitPredict

Interactor 1: PPR37 (O75864)
Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68)
Gene: PPP1R37

Interactor 2: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_6~Ras
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 691 Hs			1 189
+	Hs
		295937 PPR37_HUMAN (1-691): 2.92e-112: 355: 100.00		RASK_HUMAN (1-188): 1.61e-84: 249: 86.24
+	Hs
		295949 PPR37_HUMAN (1-691): 2.92e-112: 355: 100.00		RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90
+	Hs
		373988 CARL1_HUMAN (166-492): 7.42e-30: 128: 18.80		RASN_HUMAN (1-188): 4.47e-88: 257: 85.64
+	Hs
		375607 CARL1_HUMAN (166-492): 7.42e-30: 128: 18.80		RASK_HUMAN (1-188): 1.61e-84: 249: 86.24
+	Hs
		373928 SCRIB_HUMAN (1-316): 1.17e-26: 118: 15.45		RASN_HUMAN (1-188): 4.47e-88: 257: 85.64
+	Hs
		375514 SCRIB_HUMAN (1-316): 1.17e-26: 118: 15.45		RASK_HUMAN (1-188): 1.61e-84: 249: 86.24
+	Hs
		976329 CARL1_HUMAN (166-492): 7.42e-30: 128: 18.80		RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90
+	Hs
		976264 SCRIB_HUMAN (1-316): 1.17e-26: 118: 15.45		RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90
+	Hs
		374598 SCRIB_HUMAN (1-316): 1.17e-26: 118: 15.45		RASH_HUMAN (16-189): 6.27e-73: 219: 100.00
+	At
		1020244 BRL2_ARATH (257-547): 1.14e-23: 109: 11.35		RAB1C_ARATH (4-180): 8.99e-72: 217: 30.73