Protein: CARL1
F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)

Gene: CARL1, CARMIL1
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q5VZK9

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization
GO:0016477 - cell migration
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

866713

CAZA2
F-actin-capping protein subunit alpha-2

5

8

High-throughput

0.925

High

354719

PAK4
Serine/threonine-protein kinase PAK 4

3

6

High-throughput

0.861

High

867200

CAPZB
F-actin-capping protein subunit beta

3

4

High-throughput

0.839

High

1219707

PAK5
Serine/threonine-protein kinase PAK 5

2

9

High-throughput

0.811

High

436683

KPCB
Protein kinase C beta type

2

7

High-throughput

0.737

High

915106

CAZA1
F-actin-capping protein subunit alpha-1

1

8

High-throughput

0.691

High

373988

RASN
GTPase NRas

1

11

High-throughput

0.618

High

375607

RASK
GTPase KRas

1

11

High-throughput

0.618

High

581106

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.618

High

601327

RHOQ
Rho-related GTP-binding protein RhoQ

1

14

High-throughput

0.618

High

953503

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.618

High

955284

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.618

High

976329

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.618

High

978077

RHOB
Rho-related GTP-binding protein RhoB

1

12

High-throughput

0.618

High

988437

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.618

High

1015517

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.618

High

1144955

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.618

High

1219701

RHOJ
Rho-related GTP-binding protein RhoJ

1

13

High-throughput

0.618

High

1219689

PIANP
PILR alpha-associated neural protein

2

0

High-throughput

0.602

High

1219699

GAN
Gigaxonin

1

0

High-throughput

0.586

High

1219690

SH2D3
SH2 domain-containing protein 3C

2

6

High-throughput

0.571

High

1026425

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.536

High

1219687

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.536

High

1219703

CHODL
Chondrolectin

1

1

High-throughput

0.536

High

1219704

E41L5
Band 4.1-like protein 5

1

3

High-throughput

0.536

High

378629

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

726665

SDC4
Syndecan-4

1

0

High-throughput

0.513

High

1219685

PARM1
Prostate androgen-regulated mucin-like protein 1

1

0

High-throughput

0.513

High

226069

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

440115

LCK
Tyrosine-protein kinase Lck

1

4

High-throughput

0.479

High

463581

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

556146

CADH1
Cadherin-1

1

5

High-throughput

0.479

High

642928

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.479

High

710298

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.479

High

730663

1433S
14-3-3 protein sigma

1

13

High-throughput

0.479

High

772849

MYH9
Myosin-9

1

5

High-throughput

0.479

High

966452

1433G
14-3-3 protein gamma

1

13

High-throughput

0.479

High

1049404

1433F
14-3-3 protein eta

1

13

High-throughput

0.479

High

1138305

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1219688

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1219696

SH3K1
SH3 domain-containing kinase-binding protein 1

1

5

High-throughput

0.479

High

1219697

BICD1
Protein bicaudal D homolog 1

1

10

High-throughput

0.479

High

1219700

CHM4B
Charged multivesicular body protein 4b

1

4

High-throughput

0.479

High

1219702

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

1219708

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

341962

CEP43
Centrosomal protein 43

1

0

High-throughput

0.458

High

459631

PROF1
Profilin-1

1

0

High-throughput

0.458

High

1219691

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1219695

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

722871

SSR2
Somatostatin receptor type 2

1

1

High-throughput

0.445

High

854540

S15A1
Solute carrier family 15 member 1

1

2

High-throughput

0.445

High

859864

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.445

High

1219692

DNJB8
DnaJ homolog subfamily B member 8

1

5

High-throughput

0.445

High

1219698

CEP63
Centrosomal protein of 63 kDa

1

14

High-throughput

0.445

High

293831

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

596153

H12
Histone H1.2

1

2

High-throughput

0.437

High

695683

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

1219686

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1219709

XPO7
Exportin-7

1

6

High-throughput

0.437

High

183939

S22A2
Solute carrier family 22 member 2

1

0

High-throughput

0.426

High

1219694

CLC4C
C-type lectin domain family 4 member C

1

0

High-throughput

0.426

High

1219693

ZPLD1
Zona pellucida-like domain-containing protein 1

2

0

High-throughput

0.328

High

1219706

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

1219705

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1219710

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025