HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 538
+	Hs
		134816 MTA2_HUMAN (1-668): 0: 776: 100.00		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		295970 MTA2_HUMAN (1-668): 0: 776: 100.00		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		853588 MTA1_HUMAN (1-668): 0: 704: 56.24		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		134890 MTA1_HUMAN (1-668): 0: 704: 56.24		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		131430 MTA1_HUMAN (1-668): 0: 704: 56.24		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		853695 MTA3_HUMAN (1-570): 0: 660: 64.24		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		168665 MTA3_HUMAN (1-570): 0: 660: 64.24		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		91456 E7EQY4_HUMAN (1-500): 0: 614: 69.38		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		131502 Q9BRL8_HUMAN (448-668): 6.32e-57: 195: 34.23		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91