HitPredict

Interactor 1: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2

Interactor 2: PRG3 (Q9Y2Y8)
Proteoglycan 3 (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH)
Gene: PRG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EGF~Lectin_C, LRR_8~Lectin_C
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1529 Hs			1 225
+	Hs
		532909 NOTC1_HUMAN (1249-1526): 7.72e-37: 154: 19.64		PRG2_HUMAN (13-225): 9.19e-45: 150: 46.98
+	Hs
		1292818 JAG2_HUMAN (1214-1529): 6.78e-29: 128: 15.68		PGCB_HUMAN (69-224): 5.59e-46: 164: 21.56
+	Hs
		533105 NOTC3_HUMAN (1124-1529): 7.25e-32: 138: 16.67		PRG2_HUMAN (13-225): 9.19e-45: 150: 46.98
+	Hs
		533110 JAG2_HUMAN (1214-1529): 6.78e-29: 128: 15.68		PRG2_HUMAN (13-225): 9.19e-45: 150: 46.98
+	Hs
		980579 NOTC2_HUMAN (859-1092): 1.06e-16: 88.7: 21.90		PRG3_HUMAN (1-225): 2.3e-55: 178: 100.00
+	Hs
		532932 NOTC2_HUMAN (859-1092): 1.06e-16: 88.7: 21.90		PRG2_HUMAN (13-225): 9.19e-45: 150: 46.98
+	Hs
		417469 NOTC2_HUMAN (859-1092): 1.06e-16: 88.7: 21.90		FCER2_HUMAN (19-223): 1.04e-37: 135: 18.64