HitPredict

Interactor 1: ATG12 (O94817)
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)
Gene: ATG12

Interactor 2: ATG10 (Q9H0Y0)
Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)
Gene: ATG10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	17353931, 26186194, 28514442, 33961781, 16963840
Identification Methods	affinity chromatography technology, comigration in sds page, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, covalent binding, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0016236 - macroautophagy
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 220
+	Mm
		1246815 ATG12_MOUSE (1-140): 1.08e-73: 218: 88.65		ATG10_MOUSE (3-216): 8.99e-107: 307: 80.84
+	Hs
		296769 ATG12_HUMAN (1-140): 2.32e-76: 224: 100.00		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Mm
		1321682 ATG12_MOUSE (1-140): 1.08e-73: 218: 88.65		ATG3_MOUSE (54-210): 2.12e-51: 170: 18.63
+	Rn
		1103290 ATG12_RAT (1-140): 3.09e-70: 209: 85.11		ATG3_RAT (56-210): 9.25e-51: 168: 18.87
+	At
		1013370 AT12B_ARATH (43-140): 1.13e-45: 145: 42.86		ATG3_ARATH (34-209): 5.8e-57: 184: 13.26
+	Sc
		748356 ATG12_YEAST (28-140): 5.52e-36: 123: 23.53		ATG3_YEAST (39-209): 1.69e-26: 105: 13.30