HitPredict

Interactor 1: TOM70 (O94826)
Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70)
Gene: TOMM70

Interactor 2: TTC28 (Q96AY4)
Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)
Gene: TTC28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.595

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_1~TPR_12, TPR_1~TPR_7, TPR_12~TPR_8, TPR_7~TPR_8
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 608 Hs			1 2481
+	Hs
		174501 TOM70_HUMAN (1-608): 1.09e-91: 296: 100.00		OGT1_HUMAN (31-419): 2.66e-26: 120: 12.81
+	Sc
		422985 TOM70_YEAST (54-608): 1.02e-53: 195: 21.66		STI1_YEAST (2-309): 1.34e-21: 103: 14.83
+	Hs
		174743 OGT1_HUMAN (44-274): 2.25e-15: 82: 12.93		PPP5_HUMAN (23-224): 1.13e-46: 178: 21.36
+	Hs
		684549 STIP1_HUMAN (63-307): 4.79e-12: 70.8: 15.79		PPP5_HUMAN (23-224): 1.13e-46: 178: 21.36
+	Hs
		858598 PPP5_HUMAN (110-213): 1.09e-11: 69.3: 35.58		PPP5_HUMAN (23-224): 1.13e-46: 178: 21.36
+	Hs
		213490 STIP1_HUMAN (63-307): 4.79e-12: 70.8: 15.79		SGTA_HUMAN (45-182): 7.21e-48: 176: 29.79
+	At
		1280893 SPY_ARATH (36-304): 1.77e-18: 91.6: 10.83		SPY_ARATH (12-500): 4.76e-35: 148: 12.02
+	Mm
		1186529 OGT1_MOUSE (36-350): 6.91e-23: 105: 12.98		NPHP3_MOUSE (203-519): 2.53e-23: 111: 18.46
+	Hs
		174451 OGT1_HUMAN (44-274): 2.25e-15: 82: 12.93		OGT1_HUMAN (31-419): 2.66e-26: 120: 12.81
+	Hs
		175003 OGT1_HUMAN (44-274): 2.25e-15: 82: 12.93		NPHP3_HUMAN (203-506): 2.6e-23: 111: 18.55
+	Hs
		175137 DNJC7_HUMAN (115-245): 1.18e-10: 66.2: 32.82		OGT1_HUMAN (31-419): 2.66e-26: 120: 12.81
+	Hs
		685029 RPAP3_HUMAN (214-600): 9.89e-20: 95.4: 16.46		STIP1_HUMAN (13-280): 9.62e-14: 78.7: 11.30
+	Hs
		174456 OGT1_HUMAN (44-274): 2.25e-15: 82: 12.93		KDM6A_HUMAN (34-462): 8.53e-15: 83.3: 12.73
+	Hs
		684824 STIP1_HUMAN (63-307): 4.79e-12: 70.8: 15.79		CTR9_HUMAN (44-473): 3.69e-18: 94.1: 11.75
+	Hs
		174661 OGT1_HUMAN (44-274): 2.25e-15: 82: 12.93		STIP1_HUMAN (13-280): 9.62e-14: 78.7: 11.30
+	Hs
		684432 STIP1_HUMAN (63-307): 4.79e-12: 70.8: 15.79		STIP1_HUMAN (13-280): 9.62e-14: 78.7: 11.30
+	Hs
		684975 DNJC7_HUMAN (115-245): 1.18e-10: 66.2: 32.82		STIP1_HUMAN (13-280): 9.62e-14: 78.7: 11.30