HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 696 Hs			1 247
+	Hs
		893865 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		893862 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		564469 RHOQ_HUMAN (10-213): 9.06e-84: 264: 37.68		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		893927 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		214174 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		892304 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904428 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		214224 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		904422 RB11A_HUMAN (5-250): 9.13e-72: 233: 17.67		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		909599 RB11B_HUMAN (5-251): 2.12e-69: 227: 17.13		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		545303 RAC2_HUMAN (12-219): 3.63e-71: 231: 36.97		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		892302 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		904607 RB11B_HUMAN (5-251): 2.12e-69: 227: 17.13		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		564472 RHOQ_HUMAN (10-213): 9.06e-84: 264: 37.68		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		214204 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		214100 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		925173 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683235 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		892309 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		927083 RB11B_HUMAN (5-251): 2.12e-69: 227: 17.13		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59