HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 189
+	Hs
		297806 K0754_HUMAN (1-3515): 0: 1797: 100.00		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		297829 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		164548 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		164620 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		164547 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		164591 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		350082 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		963331 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		348621 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349252 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914014 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		895043 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		349963 UTRN_HUMAN (1888-3408): 5.82e-46: 186: 10.65		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		809121 UTRN_HUMAN (1888-3408): 5.82e-46: 186: 10.65		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		350157 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1045419 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		348654 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349308 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914061 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		348668 GOGB1_HUMAN (2376-3513): 6.18e-27: 124: 7.95		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00