HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 193
+	Hs
		297820 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		297823 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		297827 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		297812 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		297822 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		297819 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		164593 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		164599 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		164556 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		164602 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		164590 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		164598 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		164589 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		900386 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		925201 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		436258 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		893910 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		545327 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		915613 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		892322 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54