HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 196
+	Hs
		297823 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		297820 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		297812 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		297809 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		297827 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		297819 K0754_HUMAN (1-3515): 0: 1797: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		120250 K0754_HUMAN (1-3515): 0: 1797: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		120289 SPTB1_HUMAN (1491-3124): 3.29e-104: 377: 15.78		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		164599 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		164593 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		164598 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		164556 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		164602 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		164589 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		164590 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		164564 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120207 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		545327 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436258 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		120393 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98