HitPredict

Interactor 1: FARP2 (O94887)
FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)
Gene: FARP2

Interactor 2: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1054 Hs			1 832
+	Hs
		299289 FARP2_HUMAN (1-1054): 0: 847: 100.00		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		883686 FARP1_HUMAN (1-1039): 0: 737: 52.90		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		1330900 FARP1_HUMAN (1-1039): 0: 737: 52.90		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		883679 E41L3_HUMAN (39-589): 1.93e-114: 381: 29.19		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		1330892 E41L3_HUMAN (39-589): 1.93e-114: 381: 29.19		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		965179 FARP1_HUMAN (1-1039): 0: 737: 52.90		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		1021479 FARP1_HUMAN (1-1039): 0: 737: 52.90		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		640287 PTN3_HUMAN (25-508): 1.77e-100: 339: 25.00		ANR50_HUMAN (353-788): 9.53e-101: 343: 24.36
+	Hs
		965178 E41L3_HUMAN (39-589): 1.93e-114: 381: 29.19		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		547010 EZRI_HUMAN (40-577): 2e-94: 314: 17.79		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		640286 PTN3_HUMAN (25-508): 1.77e-100: 339: 25.00		KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63
+	Hs
		1336475 E41LA_HUMAN (41-556): 2.18e-97: 325: 23.96		KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63
+	Hs
		547272 EZRI_HUMAN (40-577): 2e-94: 314: 17.79		KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63
+	Hs
		201750 EZRI_HUMAN (40-577): 2e-94: 314: 17.79		RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94
+	Hs
		1021466 E41LA_HUMAN (41-556): 2.18e-97: 325: 23.96		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		547029 EZRI_HUMAN (40-577): 2e-94: 314: 17.79		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		257705 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		ANR17_HUMAN (384-541): 2.36e-20: 99.6: 14.47
+	Hs
		1219853 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		ANKH1_HUMAN (384-541): 3.69e-19: 95.3: 14.47
+	Hs
		166880 EZRI_HUMAN (40-577): 2e-94: 314: 17.79		ANR28_HUMAN (252-539): 5.33e-14: 78.4: 10.62