Protein: TRI26
Tripartite motif-containing protein 26 (EC 2.3.2.27) (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173)

Gene: TRI26, TRIM26
Organism: Homo sapiens
Interactions: 197
UniProt ID: Q12899

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1089190

TRI26
Tripartite motif-containing protein 26

3

16

Small-scale

0.852

High

1089232

RNF10
E3 ubiquitin-protein ligase RNF10

2

1

High-throughput

0.817

High

315523

RECQ4
ATP-dependent DNA helicase Q4

2

11

High-throughput

0.754

High

1089254

DDRGK
DDRGK domain-containing protein 1

5

1

High-throughput

0.712

High

1089273

THAP1
THAP domain-containing protein 1

4

2

High-throughput

0.700

High

1089242

TRI41
E3 ubiquitin-protein ligase TRIM41

1

16

High-throughput

0.698

High

1089215

IFIX
Pyrin and HIN domain-containing protein 1

4

5

High-throughput

0.694

High

1089193

TIF1B
Transcription intermediary factor 1-beta

1

19

High-throughput

0.691

High

1061678

TLE5
TLE family member 5

3

2

High-throughput

0.675

High

230307

CREB3
Cyclic AMP-responsive element-binding protein 3

3

4

High-throughput

0.667

High

1089236

ZBT38
Zinc finger and BTB domain-containing protein 38

3

20

High-throughput

0.667

High

1089249

ZN707
Zinc finger protein 707

3

20

High-throughput

0.667

High

848372

MAGA6
Melanoma-associated antigen 6

3

15

High-throughput

0.661

High

1089283

DDX41
Probable ATP-dependent RNA helicase DDX41

1

9

Small-scale

0.647

High

872267

SOX2
Transcription factor SOX-2

2

5

High-throughput

0.639

High

887416

CEBPD
CCAAT/enhancer-binding protein delta

2

4

Small-scale

0.639

High

1089202

ZN169
Zinc finger protein 169

2

17

High-throughput

0.628

High

1089230

YAF2
YY1-associated factor 2

2

2

High-throughput

0.628

High

1089275

H2AW
Core histone macro-H2A.2

2

6

High-throughput

0.628

High

1089284

ZN223
Zinc finger protein 223

2

17

High-throughput

0.628

High

957067

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.619

High

1026880

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

1

Small-scale

0.618

High

1089219

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

1089235

CGAS
Cyclic GMP-AMP synthase

1

3

High-throughput

0.618

High

1089264

THAP7
THAP domain-containing protein 7

2

2

High-throughput

0.611

High

277666

H2AY
Core histone macro-H2A.1

2

6

High-throughput

0.606

High

329447

EPN2
Epsin-2

2

4

High-throughput

0.606

High

1089225

BIVM
Basic immunoglobulin-like variable motif-containing protein

2

1

High-throughput

0.606

High

139522

PESC
Pescadillo homolog

2

0

High-throughput

0.602

High

1089217

L2GL2
LLGL scribble cell polarity complex component 2

2

0

High-throughput

0.602

High

1089257

DACH2
Dachshund homolog 2

2

0

High-throughput

0.602

High

1089216

CAVN1
Caveolae-associated protein 1

2

1

High-throughput

0.601

High

507891

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

11

High-throughput

0.595

High

1089211

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

2

20

Small-scale

0.586

High

1089276

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

7

High-throughput

0.586

High

241531

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.584

High

992716

RACK1
Small ribosomal subunit protein RACK1

2

5

Small-scale

0.584

High

1089210

LARP7
La-related protein 7

2

12

High-throughput

0.584

High

1089221

MEPCE
7SK snRNA methylphosphate capping enzyme

2

1

High-throughput

0.584

High

1089270

ANLN
Anillin

2

3

High-throughput

0.584

High

1089201

IRF3
Interferon regulatory factor 3

1

11

Small-scale

0.578

High

396004

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

908199

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

9

High-throughput

0.571

High

1051211

KPCZ
Protein kinase C zeta type

2

9

High-throughput

0.571

High

764702

CTNB1
Catenin beta-1

1

9

Small-scale

0.561

High

1089234

BEND7
BEN domain-containing protein 7

2

1

High-throughput

0.553

High

1081359

INCA1
Protein INCA1

1

1

Small-scale

0.552

High

906650

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

High-throughput

0.541

High

908740

MAT1
CDK-activating kinase assembly factor MAT1

1

7

High-throughput

0.541

High

982171

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.541

High

1089205

RABE1
Rab GTPase-binding effector protein 1

1

8

High-throughput

0.541

High

1089265

RN126
E3 ubiquitin-protein ligase RNF126

1

3

High-throughput

0.541

High

1089267

PHF7
E3 ubiquitin-protein ligase PHF7

1

7

High-throughput

0.541

High

67429

GOG8A
Golgin subfamily A member 8A

1

11

High-throughput

0.536

High

74473

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

5

High-throughput

0.536

High

168678

CSKP
Peripheral plasma membrane protein CASK

1

6

High-throughput

0.536

High

541980

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

842346

RL35
Large ribosomal subunit protein uL29

1

2

High-throughput

0.536

High

967413

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.536

High

1089194

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.536

High

1089196

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

5

High-throughput

0.536

High

1089200

ZN460
Zinc finger protein 460

1

19

High-throughput

0.536

High

1089212

CE162
Centrosomal protein of 162 kDa

1

13

High-throughput

0.536

High

1089218

KLC3
Kinesin light chain 3

1

3

High-throughput

0.536

High

1089227

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1089229

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

6

High-throughput

0.536

High

1089239

ZN418
Zinc finger protein 418

1

14

High-throughput

0.536

High

1089240

PHF10
PHD finger protein 10

1

4

High-throughput

0.536

High

1089248

ARRD3
Arrestin domain-containing protein 3

1

2

High-throughput

0.536

High

1089250

ZN689
Zinc finger protein 689

1

20

High-throughput

0.536

High

1089269

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

1

High-throughput

0.536

High

1089286

PHF8
Histone lysine demethylase PHF8

1

1

High-throughput

0.536

High

116893

I6L9I8
EPN3 protein

1

3

High-throughput

0.515

High

1089206

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

Small-scale

0.513

High

75759

B3KW44
tRNA N(3)-cytidine methyltransferase

1

0

High-throughput

0.513

High

884076

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

1089253

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1089282

MSRA
Mitochondrial peptide methionine sulfoxide reductase

1

0

High-throughput

0.513

High

790039

ZEB1
Zinc finger E-box-binding homeobox 1

1

20

Small-scale

0.501

High

964253

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

477162

ACM5
Muscarinic acetylcholine receptor M5

1

1

High-throughput

0.489

High

871166

TFPI2
Tissue factor pathway inhibitor 2

1

4

High-throughput

0.489

High

1089199

RBM39
RNA-binding protein 39

1

9

High-throughput

0.489

High

1089222

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

5

High-throughput

0.489

High

1089226

PNM8A
Paraneoplastic antigen-like protein 8A

1

3

High-throughput

0.489

High

1089262

UTP23
rRNA-processing protein UTP23 homolog

1

1

High-throughput

0.489

High

1089274

MTCH1
Mitochondrial carrier homolog 1

1

7

High-throughput

0.489

High

1089277

PCD10
Protocadherin-10

1

1

High-throughput

0.489

High

385693

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

19

High-throughput

0.481

High

853462

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

20

High-throughput

0.481

High

1040786

MECOM
Histone-lysine N-methyltransferase MECOM

1

20

High-throughput

0.481

High

1089252

OTUB2
Ubiquitin thioesterase OTUB2

1

4

High-throughput

0.481

High

1089268

EPN3
Epsin-3

1

3

High-throughput

0.481

High

171869

ZN263
Zinc finger protein 263

1

19

Small-scale

0.479

High

172754

XPO1
Exportin-1

1

3

High-throughput

0.479

High

215300

TXNL1
Thioredoxin-like protein 1

1

8

Small-scale

0.479

High

248291

HBP1
HMG box-containing protein 1

1

5

High-throughput

0.479

High

343363

SNP29
Synaptosomal-associated protein 29

1

1

Small-scale

0.479

High

358679

LDHA
L-lactate dehydrogenase A chain

1

2

Small-scale

0.479

High

385095

K1C14
Keratin, type I cytoskeletal 14

1

15

Small-scale

0.479

High

390030

ALBU
Albumin

1

4

Small-scale

0.479

High

407283

K2C6B
Keratin, type II cytoskeletal 6B

1

13

Small-scale

0.479

High

413727

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

436855

K1C18
Keratin, type I cytoskeletal 18

1

13

Small-scale

0.479

High

445849

ENOA
Alpha-enolase

1

1

Small-scale

0.479

High

447747

TPM3
Tropomyosin alpha-3 chain

1

5

Small-scale

0.479

High

456713

ANXA2
Annexin A2

1

6

Small-scale

0.479

High

475567

K1C19
Keratin, type I cytoskeletal 19

1

13

Small-scale

0.479

High

476140

ANXA5
Annexin A5

1

5

Small-scale

0.479

High

476306

K1C16
Keratin, type I cytoskeletal 16

1

13

Small-scale

0.479

High

482894

TPM1
Tropomyosin alpha-1 chain

1

4

Small-scale

0.479

High

483447

ANXA4
Annexin A4

1

5

Small-scale

0.479

High

537064

HSP7C
Heat shock cognate 71 kDa protein

1

10

Small-scale

0.479

High

551016

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.479

High

584863

NQO1
NAD(P)H dehydrogenase [quinone] 1

1

1

Small-scale

0.479

High

586662

RS2
Small ribosomal subunit protein uS5

1

2

Small-scale

0.479

High

609665

LEG3
Galectin-3

1

14

Small-scale

0.479

High

612620

RL7
Large ribosomal subunit protein uL30

1

2

Small-scale

0.479

High

618684

ML12A
Myosin regulatory light chain 12A

1

2

Small-scale

0.479

High

658140

RS3
Small ribosomal subunit protein uS3

1

4

Small-scale

0.479

High

675011

TNR6
Tumor necrosis factor receptor superfamily member 6

1

3

High-throughput

0.479

High

680853

PSA1
Proteasome subunit alpha type-1

1

4

Small-scale

0.479

High

690240

STOM
Stomatin

1

6

Small-scale

0.479

High

749472

C2TA
MHC class II transactivator

1

17

Small-scale

0.479

High

766500

PHB1
Prohibitin 1

1

6

Small-scale

0.479

High

813456

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

2

Small-scale

0.479

High

823835

PBX1
Pre-B-cell leukemia transcription factor 1

1

1

Small-scale

0.479

High

828762

MDHM
Malate dehydrogenase, mitochondrial

1

2

Small-scale

0.479

High

952786

ACTB
Actin, cytoplasmic 1

1

12

Small-scale

0.479

High

959752

RS3A
Small ribosomal subunit protein eS1

1

3

Small-scale

0.479

High

960094

RL26
Large ribosomal subunit protein uL24

1

2

High-throughput

0.479

High

971457

1433E
14-3-3 protein epsilon

1

2

Small-scale

0.479

High

972379

RS14
Small ribosomal subunit protein uS11

1

2

High-throughput

0.479

High

975661

RL7A
Large ribosomal subunit protein eL8

1

2

Small-scale

0.479

High

978897

RS6
Small ribosomal subunit protein eS6

1

2

Small-scale

0.479

High

983465

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

Small-scale

0.479

High

995410

TPM4
Tropomyosin alpha-4 chain

1

4

Small-scale

0.479

High

996123

EF1A1
Elongation factor 1-alpha 1

1

2

Small-scale

0.479

High

1057130

PRDX1
Peroxiredoxin-1

1

6

Small-scale

0.479

High

1089191

TP4A2
Protein tyrosine phosphatase type IVA 2

1

1

High-throughput

0.479

High

1089192

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

4

Small-scale

0.479

High

1089195

SQSTM
Sequestosome-1

1

7

High-throughput

0.479

High

1089197

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1089198

DCTN1
Dynactin subunit 1

1

8

High-throughput

0.479

High

1089204

IF4H
Eukaryotic translation initiation factor 4H

1

10

Small-scale

0.479

High

1089207

STK11
Serine/threonine-protein kinase STK11

1

1

Small-scale

0.479

High

1089208

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1089209

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

3

Small-scale

0.479

High

1089214

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.479

High

1089223

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

1089224

CNTRL
Centriolin

1

9

High-throughput

0.479

High

1089233

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

17

High-throughput

0.479

High

1089237

RIN3
Ras and Rab interactor 3

1

6

High-throughput

0.479

High

1089238

FBF1
Fas-binding factor 1

1

11

High-throughput

0.479

High

1089243

DNJC9
DnaJ homolog subfamily C member 9

1

3

Small-scale

0.479

High

1089244

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

2

Small-scale

0.479

High

1089245

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1089246

FBXW7
F-box/WD repeat-containing protein 7

1

5

High-throughput

0.479

High

1089247

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.479

High

1089260

RING2
E3 ubiquitin-protein ligase RING2

1

17

High-throughput

0.479

High

1089266

RBM4
RNA-binding protein 4

1

10

Small-scale

0.479

High

1089271

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

3

Small-scale

0.479

High

1089272

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1089280

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.479

High

1089281

UBQL2
Ubiquilin-2

1

11

High-throughput

0.479

High

1089285

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.479

High

1089288

SRRM2
Serine/arginine repetitive matrix protein 2

1

4

High-throughput

0.479

High

1089291

NEMO
NF-kappa-B essential modulator

1

14

Small-scale

0.479

High

213458

CTIF
CBP80/20-dependent translation initiation factor

1

0

High-throughput

0.458

High

215422

TPD54
Tumor protein D54

1

0

Small-scale

0.458

High

483331

CLCB
Clathrin light chain B

1

0

Small-scale

0.458

High

784784

VATE1
V-type proton ATPase subunit E 1

1

0

Small-scale

0.458

High

874148

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

Small-scale

0.458

High

1054576

PSME1
Proteasome activator complex subunit 1

1

0

Small-scale

0.458

High

1089203

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1089251

CC124
Coiled-coil domain-containing protein 124

1

0

Small-scale

0.458

High

1089259

PNKP
Bifunctional polynucleotide phosphatase/kinase

1

0

Small-scale

0.458

High

1089261

PYM1
Partner of Y14 and mago

1

0

Small-scale

0.458

High

1089278

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.458

High

1089289

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

1089290

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

765455

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.445

High

1089263

ZN577
Zinc finger protein 577

1

20

High-throughput

0.445

High

1089220

CE128
Centrosomal protein of 128 kDa

1

11

High-throughput

0.437

High

1089228

LCA5
Lebercilin

1

11

High-throughput

0.437

High

1089231

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

1089241

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.437

High

1089279

CATZ
Cathepsin Z

1

2

Small-scale

0.437

High

844763

EAA1
Excitatory amino acid transporter 1

1

2

High-throughput

0.407

High

1089255

MF14A
Hippocampus abundant transcript 1 protein

1

1

High-throughput

0.407

High

1089258

DCR1C
Protein artemis

2

0

High-throughput

0.318

High

1089256

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

571422

GLU2B
Glucosidase 2 subunit beta

1

0

Small-scale

0.249

Low

1089213

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

1089287

XCT
Cystine/glutamate transporter

1

0

Small-scale

0.249

Low

516090

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025