HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21343306
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 618
+	Hs
		299875 ERLN2_HUMAN (1-339): 5.38e-116: 341: 100.00		RAB8A_HUMAN (5-196): 2.97e-71: 230: 18.56
+	Hs
		299876 ERLN2_HUMAN (1-339): 5.38e-116: 341: 100.00		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Hs
		266141 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83
+	Hs
		266136 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RAB8A_HUMAN (5-196): 2.97e-71: 230: 18.56
+	Hs
		266137 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Hs
		646166 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83
+	Dm
		185509 Q9VWL0_DROME (7-250): 3.46e-67: 216: 18.15		O18332_DROME (5-182): 2.5e-75: 240: 20.00
+	Hs
		646158 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAB8A_HUMAN (5-196): 2.97e-71: 230: 18.56
+	Hs
		545212 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAC2_HUMAN (3-185): 6.9e-70: 226: 23.86
+	Hs
		646156 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAC3_HUMAN (3-168): 4.28e-70: 226: 23.89
+	Hs
		646171 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOG_HUMAN (3-170): 8.87e-68: 220: 25.28
+	Hs
		646160 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Hs
		951448 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		RHOG_HUMAN (3-170): 8.87e-68: 220: 25.28
+	Hs
		266139 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RHOB_HUMAN (6-168): 6.46e-10: 60.8: 25.99
+	Hs
		120306 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOD_HUMAN (3-171): 2.64e-11: 65.5: 27.87
+	Hs
		646307 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOF_HUMAN (2-167): 3.85e-11: 64.7: 28.33
+	Hs
		646164 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOB_HUMAN (6-168): 6.46e-10: 60.8: 25.99
+	Hs
		564417 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOQ_HUMAN (5-169): 8.64e-09: 57.8: 27.37