HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 249
+	Hs
		266267 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		266084 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		646324 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Mm
		1265157 PODO_MOUSE (6-260): 4.22e-62: 204: 16.54		VAPA_MOUSE (1-249): 2.59e-99: 291: 97.19
+	Hs
		73291 B4E2V5_HUMAN (21-254): 6.78e-62: 199: 16.74		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1349640 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		91340 E5RHW4_HUMAN (1-338): 6.12e-115: 338: 100.00		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34