HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: ITM2B (Q9Y287)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34446781
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 266
+	Rn
		78161 ERLN2_RAT (1-339): 5.47e-118: 346: 97.35		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Hs
		266274 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		ITM2B_HUMAN (1-266): 1.45e-148: 417: 100.00
+	Mm
		292584 PODO_MOUSE (6-260): 4.22e-62: 204: 16.54		ITM2B_MOUSE (1-266): 3.23e-150: 421: 95.49
+	Rn
		1116237 STML2_RAT (20-319): 2.5e-58: 193: 14.24		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Rn
		1140191 PHB2_RAT (5-269): 1.49e-57: 190: 13.77		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Hs
		1356209 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		ITM2B_HUMAN (1-266): 1.45e-148: 417: 100.00