HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	12039962, 35785414
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 920
+	Hs
		487741 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		487530 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		487776 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		174572 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		300025 PRP6_HUMAN (1-941): 0: 610: 100.00		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		370376 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		369613 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		1190470 TT21B_HUMAN (258-935): 6.29e-42: 168: 13.15		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		377572 TTC28_HUMAN (441-940): 3.1e-38: 157: 7.45		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		369839 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		370484 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		1057989 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		174531 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		1160955 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		611462 PRP39_HUMAN (425-927): 1.16e-23: 109: 15.92		NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71
+	Hs
		1269676 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		175077 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Mm
		1142644 CTR9_MOUSE (126-536): 5.01e-16: 85.3: 10.12		ERR2_MOUSE (467-904): 1.62e-109: 346: 23.64
+	Mm
		1142687 OGT1_MOUSE (120-352): 4.66e-10: 65.7: 11.39		ERR2_MOUSE (467-904): 1.62e-109: 346: 23.64