HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	34133714, 32707033
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 499
+	Hs
		833812 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		834043 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		1044127 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		174631 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Dm
		1180640 Q7KJA9_DROME (191-711): 2.56e-67: 246: 12.66		Q9W0Q1_DROME (131-478): 5.28e-42: 162: 29.47
+	Hs
		174871 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Sc
		688541 RRP5_YEAST (276-524): 4.45e-12: 72.5: 17.28		KNS1_YEAST (146-418): 3.57e-66: 228: 39.45