HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: PRP31 (Q8WWY3)
U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31)
Gene: PRPF31

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.710

The method score is based on:

Property Details
Experiments 37071682, 16723661, 22365833, 33961781
Identification Methods cross-linking study, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 941
Hs

1 499
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024