HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 915
+	Mm
		88347 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SAFB1_MOUSE (1-915): 5.21e-105: 349: 82.96
+	Mm
		1194511 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SAFB2_MOUSE (1-915): 3.08e-89: 307: 52.31
+	Hs
		268082 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SAFB2_HUMAN (1-906): 1.05e-88: 305: 68.34
+	Hs
		268143 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		NIPBL_HUMAN (106-890): 6.43e-61: 228: 10.72
+	Mm
		1154100 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		NIPBL_MOUSE (106-890): 2.07e-58: 221: 10.72
+	Hs
		268306 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SLTM_HUMAN (29-828): 1.63e-50: 195: 30.24
+	Mm
		1208465 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SLTM_MOUSE (29-828): 5.81e-48: 187: 26.06
+	Mm
		665768 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PABP1_MOUSE (258-499): 9.95e-38: 152: 14.51
+	Mm
		1265608 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PLEC_MOUSE (37-756): 3.97e-35: 147: 12.14
+	Hs
		1345855 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		MDN1_HUMAN (63-707): 1.6e-64: 239: 11.64
+	Hs
		903196 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		1031492 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		516438 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		198952 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		RFOX2_HUMAN (301-501): 9.17e-31: 127: 21.80
+	Hs
		516733 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51