HitPredict

Interactor 1: DKK1 (O94907)
Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK)
Gene: DKK1

Interactor 2: KREM1 (Q96MU8)
Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)
Gene: KREMEN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 17804805, 27524201
Identification Methods anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0030279 - negative regulation of ossification
GO:0060173 - limb development
GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 266
Hs

1 473
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024